Triglyceride glucose index for the detection of the severity of coronary artery disease in different glucose metabolic states in patients with coronary heart disease: a …

J Su, Z Li, M Huang, Y Wang, T Yang, M Ma… - Cardiovascular …, 2022 - Springer
Abstract Background Triglyceride glucose (TyG) index is a new marker associated with
atherosclerosis. This study aimed to assess the association between TyG index and the …

Associations of genetic susceptibility and healthy lifestyle with incidence of coronary heart disease and stroke in individuals with hypertension

M Wang, S Brage, SJ Sharp, S Luo… - European journal of …, 2022 - academic.oup.com
Aims This study explored the associations of genetic susceptibility and adherence to a
healthy lifestyle with incident coronary heart disease (CHD) and stroke in individuals with …

Physicians' misperceived cardiovascular risk and therapeutic inertia as determinants of low LDL-cholesterol targets achievement in diabetes

ML Morieri, O Lamacchia, E Manzato… - Cardiovascular …, 2022 - Springer
Background Greater efforts are needed to overcome the worldwide reported low
achievement of LDL-c targets. This survey aimed to dissect whether and how the physician …

Development of risk prediction models for depression combining genetic and early life risk factors

T Lu, PP Silveira, CMT Greenwood - Frontiers in neuroscience, 2023 - frontiersin.org
Background Both genetic and early life risk factors play important roles in the pathogenesis
and progression of adult depression. However, the interplay between these risk factors and …

Prognostic value of a polygenic risk score for coronary heart disease in individuals aged 70 years and older

JT Neumann, M Riaz, A Bakshi… - Circulation: Genomic …, 2022 - Am Heart Assoc
Background: The use of a polygenic risk score (PRS) to improve risk prediction of coronary
heart disease (CHD) events has been demonstrated to have clinical utility in the general …

Correlation of heavy metals' exposure with the prevalence of coronary heart disease among US adults: findings of the US NHANES from 2003 to 2018

X Li, D Zhang, Y Zhao, L Kuang, H Huang… - Environmental …, 2023 - Springer
We sought to explore the association between heavy metal exposure and coronary heart
disease (CHD) based on data from the US National Health and Nutrition Examination …

Type 2 diabetes modifies the association of CAD genomic risk variants with subclinical atherosclerosis

NR Hasbani, KE Westerman, SH Kwak… - Circulation: Genomic …, 2023 - Am Heart Assoc
BACKGROUND: Individuals with type 2 diabetes (T2D) have an increased risk of coronary
artery disease (CAD), but questions remain about the underlying pathology. Identifying …

Identification of type 2 diabetes based on a ten‐gene biomarker prediction model constructed using a support vector machine algorithm

J Li, J Ding, DU Zhi, K Gu… - BioMed Research …, 2022 - Wiley Online Library
Background. Type 2 diabetes is a major health concern worldwide. The present study is
aimed at discovering effective biomarkers for an efficient diagnosis of type 2 diabetes …

Polygenic risk and coronary artery disease severity

A Sherafati, K Norland, M Naderian… - Circulation: Genomic …, 2024 - ahajournals.org
BACKGROUND: Coronary atherosclerotic burden and adverse coronary heart disease
events are related phenotypes with likely shared genetic cause. METHODS: We analyzed …

Disease patterns of coronary heart disease and type 2 diabetes harbored distinct and shared genetic architecture

H **ao, Y Ma, Z Zhou, X Li, K Ding, Y Wu, T Wu… - Cardiovascular …, 2022 - Springer
Background Coronary heart disease (CHD) and type 2 diabetes (T2D) are two complex
diseases with complex interrelationships. However, the genetic architecture of the two …