Aerosol therapy is a key modality for drug delivery to the lungs of respiratory disease
patients. Aerosol therapy improves therapeutic effects by directly targeting diseased lung …

Despite many therapeutic advancements over the past decade, the continued rise in chronic
inflammatory lung diseases incidence has driven the need to identify and develop new …

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly found in premature
infants. Excessive inflammation and oxidative stress contribute to BPD occurrence and …

Background The use of amino acids as excipients is a promising approach to improve the
physical stability and powder dispersibility of spray-dried powders for inhalation. Objectives …

Introduction: Asthma manifests as chronic airflow obstruction with persistent inflammation
and airway hyperresponsiveness. The immunomodulatory and anti-inflammatory properties …

Atorvastatin (ATO) is of the statin class and is used as an orally administered lipid-lowering
drug. ATO is a reversible synthetic competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-CoA …

Xanthoma pathogenesis is speculated to be associated with oxidized low-density lipoprotein
(ox-LDL) deposition, although this remains unclear. Most patients with diffuse plane …

Aim: Current inhaled treatments are not adequate to treat all lung diseases. In this study, a
promising nanotechnology has been developed to deliver a potential anti-inflammatory and …

Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase
inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The …

Background Diabetes induces long bone loss and aggravation of periodontitis-induced
alveolar bone loss. Simvastatin (SIM), which is a lipid-lowering agent is known to have an …