THC and CBD: Similarities and differences between siblings

N Stella - Neuron, 2023 - cell.com
Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …

Neurodevelopmental resilience and susceptibility to maternal immune activation

U Meyer - Trends in neurosciences, 2019 - cell.com
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is
implicated in various psychiatric and neurological disorders with developmental etiologies …

[HTML][HTML] The dual hit hypothesis of schizophrenia: Evidence from animal models

CGJ Guerrin, J Doorduin, IE Sommer… - … & Biobehavioral Reviews, 2021 - Elsevier
Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Opportunities for cannabis in supportive care in cancer

AS Kleckner, IR Kleckner, CS Kamen… - … in medical oncology, 2019 - journals.sagepub.com
Cannabis has the potential to modulate some of the most common and debilitating
symptoms of cancer and its treatments, including nausea and vomiting, loss of appetite, and …

Neurodevelopmental factors in schizophrenia

H Jaaro-Peled, A Sawa - Psychiatric Clinics, 2020 - psych.theclinics.com
Schizophrenia is known to be one of the most devastating and chronic mental conditions.
The onset of this syndrome, which includes heterogeneous subsets of disease conditions, is …

[HTML][HTML] CXCL12-mediated monocyte transmigration into brain perivascular space leads to neuroinflammation and memory deficit in neuropathic pain

CL Mai, Z Tan, YN Xu, JJ Zhang, ZH Huang, D Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Emerging clinical and experimental evidence demonstrates that neuroinflammation plays an
important role in cognitive impairment associated with neuropathic pain. However, how …

Phytocannabinoids and schizophrenia: Focus on adolescence as a critical window of enhanced vulnerability and opportunity for treatment

T Stark, S Di Martino, F Drago, CT Wotjak… - Pharmacological …, 2021 - Elsevier
The recent shift in socio-political debates and growing liberalization of Cannabis use across
the globe has raised concern regarding its impact on vulnerable populations such as …

Evaluation of conventional and hyaluronic acid-coated thymoquinone liposomes in an in vitro model of dry eye

E Landucci, C Mazzantini, M Calvani… - Pharmaceutics, 2023 - mdpi.com
Dry eye disease (DED) is a common ocular disorder characterized by an inadequate
lubrication of the eye by tears leading to inflammation and the alteration of the ocular …

Harmful effects of smoking cannabis: a cerebrovascular and neurological perspective

SR Archie, L Cucullo - Frontiers in pharmacology, 2019 - frontiersin.org
Apart from being used as a medicine, cannabis or marijuana is the most widely abused
recreational drug all over the world. The legalization and decriminalization of cannabis in …