Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
Electrochemotherapy: from the drawing board into medical practice
Electrochemotherapy is a local treatment of cancer employing electric pulses to improve
transmembrane transfer of cytotoxic drugs. In this paper we discuss electrochemotherapy …
transmembrane transfer of cytotoxic drugs. In this paper we discuss electrochemotherapy …
[HTML][HTML] In vitro electroporation detection methods–An overview
TB Napotnik, D Miklavčič - Bioelectrochemistry, 2018 - Elsevier
Exposing cells to an electric field leads to electroporation of the cell membrane which has
already been explored and used in a number of applications in medicine and food …
already been explored and used in a number of applications in medicine and food …
A brief overview of electroporation pulse strength–duration space: A region where additional intracellular effects are expected
JC Weaver, KC Smith, AT Esser, RS Son… - …, 2012 - Elsevier
Electroporation (EP) of outer cell membranes is widely used in research, biotechnology and
medicine. Now intracellular effects by organelle EP are of growing interest, mainly due to …
medicine. Now intracellular effects by organelle EP are of growing interest, mainly due to …
A new pulsed electric field therapy for melanoma disrupts the tumor's blood supply and causes complete remission without recurrence
We have discovered a new, ultrafast therapy for treating skin cancer that is extremely
effective with a total electric field exposure time of only 180 μsec. The application of 300 high …
effective with a total electric field exposure time of only 180 μsec. The application of 300 high …
Lipid nanopores can form a stable, ion channel-like conduction pathway in cell membrane
Cell permeabilization by electric pulses (EPs), or electroporation, has been well established
as a tool to indiscriminately increase membrane flows of water solutes down the …
as a tool to indiscriminately increase membrane flows of water solutes down the …
Electroporation of cell membranes: the fundamental effects of pulsed electric fields in food processing
G Saulis - Food Engineering Reviews, 2010 - Springer
Using of pulsed electric fields (PEF) for killing of microorganisms in liquid foods is a
promising new non-thermal food processing and preservation technology. However, to …
promising new non-thermal food processing and preservation technology. However, to …
Glioblastoma therapy: past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
Equivalent pulse parameters for electroporation
G Pucihar, J Krmelj, M Reberšek… - IEEE Transactions …, 2011 - ieeexplore.ieee.org
Electroporation-based applications require the use of specific pulse parameters for a
successful outcome. When recommended values of pulse parameters cannot be set, similar …
successful outcome. When recommended values of pulse parameters cannot be set, similar …
Electrotherapies for glioblastoma
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …