Disrobes the characterization of the periodontal diseases as multifactorial infections elicited
by a complex of bacterial species that interact with host tissues and cells. Cause of cells to …

Proteases are signaling molecules that specifically control cellular functions by cleaving
protease-activated receptors (PARs). The four known PARs are members of the large family …

Protein secretion systems are vital for prokaryotic life, as they enable bacteria to acquire
nutrients, communicate with other species, defend against biological and chemical agents …

Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

Arguably periodontitis is the most prevalent bacteria-driven chronic inflammatory disease of
the humankind. The incidence of periodontal disease has been reported to range from 30 …

Porphyromonas gingivalis secretes strong proteases called gingipains that are implicated in
periodontal pathogenesis. Protein secretion systems common to other Gram-negative …

According to the most recent classification that resulted from a 1999 international workshop
[1], diseases of the periodontium comprise a long list of conditions involving the supporting …

Discusses the role of bacterial proteinases in matrix destruction and modulation of host
responses. Evasion of host defense mechanisms; Mechanism of gingipain inference with …

Gingipains are trypsin‐like cysteine proteinases produced by Porphyromonas gingivalis, a
major causative bacterium of adult periodontitis. HRgpA (95 kDa) and RgpB (50 kDa) …

Discusses the origin and function of the cellular components in gingival crevice fluid.
Anatomical origin of the cells of the gingival crevice fluid; Presence of pathogenic plaque in …