Design of NIR-II high performance organic small molecule fluorescent probes and summary of their biomedical applications

X Liu, B Yu, Y Shen, H Cong - Coordination Chemistry Reviews, 2022 - Elsevier
Near-infrared fluorescence imaging has gained a lot of attention in biomedicine by virtue of
its high sensitivity, high specificity, and many other advantages. Moreover, near-infrared II …

Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Q **n, H Ma, H Wang, XD Zhang - Exploration, 2023 - Wiley Online Library
Heterogeneous cells are the main feature of tumors with unique genetic and phenotypic
characteristics, which can stimulate differentially the progression, metastasis, and drug …

Programmable NIR‐II Photothermal‐Enhanced Starvation‐Primed Chemodynamic Therapy using Glucose Oxidase‐Functionalized Ancient Pigment Nanosheets

C Yang, MR Younis, J Zhang, J Qu, J Lin, P Huang - Small, 2020 - Wiley Online Library
Chemodynamic therapy (CDT) has attracted considerable attention recently, but the poor
reaction kinetics restrict its practical utility in clinic. Herein, glucose oxidase (GOx) …

Second Near‐Infrared (NIR‐II) Window for Imaging‐Navigated Modulation of Brain Structure and Function

K Zhang, FR Chen, L Wang, J Hu - Small, 2023 - Wiley Online Library
For a long time, optical imaging of the deep brain with high resolution has been a challenge.
Recently, with the advance in second near‐infrared (NIR‐II) bioimaging techniques and …

Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window

X Zhang, X Li, W Shi, H Ma - Chemical Communications, 2021 - pubs.rsc.org
A nitroreductase (NTR)-activated NIR-II fluorescence probe for tumor imaging is reported.
The probe can emit fluorescence in the range of 900–1300 nm, and target hypoxic tumors …

PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools

J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

NIRF nanoprobes for cancer molecular imaging: approaching clinic

Z Hu, WH Chen, J Tian, Z Cheng - Trends in Molecular medicine, 2020 - cell.com
Near-IR fluorescence imaging (NIRFI) is a highly promising technique for improving cancer
theranostics in the era of precision medicine. Through the combination with cutting-edge …

Alkaline Phosphatase Enabled Fluorogenic Reaction and in situ Coassembly of Near-Infrared and Radioactive Nanoparticles for in vivo Imaging

Y Hu, Y Miao, J Zhang, Y Chen, L Qiu, J Lin, D Ye - Nano Letters, 2021 - ACS Publications
Smart near-infrared (NIR) fluorescence (FL) and positron emission tomography (PET)
bimodal probes have shown promise for preoperative and intraoperative imaging of tumors …

An IR820 dye–protein complex for second near‐infrared window and photoacoustic imaging

B Du, C Qu, K Qian, Y Ren, Y Li, X Cui… - Advanced Optical …, 2020 - Wiley Online Library
Recently, much attention has been focused on the development of second near‐infrared
window (NIR‐II, 1000–1700 nm) fluorescence imaging because of its reduced scattering …

Image‐guided tumor surgery: The emerging role of nanotechnology

NE Wojtynek, AM Mohs - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Surgical resection is a mainstay treatment for solid tumors. Yet, methods to distinguish
malignant from healthy tissue are primarily limited to tactile and visual cues as well as the …