Emerging open microfluidics for cell manipulation

Q Zhang, S Feng, L Lin, S Mao, JM Lin - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell manipulation is the foundation of biochemical studies, which demands user-friendly,
multifunctional and precise tools. Based on flow confinement principles, open microfluidics …

Microfluidics with fluid walls

EJ Walsh, A Feuerborn, JHR Wheeler, AN Tan… - Nature …, 2017 - nature.com
Microfluidics has great potential, but the complexity of fabricating and operating devices has
limited its use. Here we describe a method—Freestyle Fluidics—that overcomes many key …

Patterned superhydrophobic surfaces: toward a synthetic mimic of the Namib Desert beetle

L Zhai, MC Berg, FÇ Cebeci, Y Kim, JM Milwid… - Nano Letters, 2006 - ACS Publications
The present study demonstrates a surface structure that mimics the water harvesting wing
surface of the Namib Desert beetle. Hydrophilic patterns on superhydrophobic surfaces …

Suspended microfluidics

BP Casavant, E Berthier, AB Theberge… - Proceedings of the …, 2013 - pnas.org
Although the field of microfluidics has made significant progress in bringing new tools to
address biological questions, the accessibility and adoption of microfluidics within the life …

A microfluidic platform for functional testing of cancer drugs on intact tumor slices

AD Rodriguez, LF Horowitz, K Castro, H Kenerson… - Lab on a Chip, 2020 - pubs.rsc.org
Present approaches to assess cancer treatments are often inaccurate, costly, and/or
cumbersome. Functional testing platforms that use live tumor cells are a promising tool both …

Microfluidics in the “open space” for performing localized chemistry on biological interfaces

GV Kaigala, RD Lovchik… - Angewandte Chemie …, 2012 - Wiley Online Library
Local interactions between (bio) chemicals and biological interfaces play an important role
in fields ranging from surface patterning to cell toxicology. These interactions can be studied …

A microfluidic dual-well device for high-throughput single-cell capture and culture

CH Lin, YH Hsiao, HC Chang, CF Yeh, CK He… - Lab on a Chip, 2015 - pubs.rsc.org
In vitro culture of single cells facilitates biological studies by deconvoluting complications
from cell population heterogeneity. However, there is still a lack of simple yet high …

Recent advances on open fluidic systems for biomedical applications: A review

NM Oliveira, S Vilabril, MB Oliveira, RL Reis… - Materials Science and …, 2019 - Elsevier
Microfluidics has become an important tool to engineer microenvironments with high
precision, comprising devices and methods for controlling and manipulating fluids at the …

Two-dimensional open microfluidic devices by tuning the wettability on patterned superhydrophobic polymeric surface

NM Oliveira, AI Neto, W Song… - Applied physics express, 2010 - iopscience.iop.org
We present a simple and economical method to produce a potential open microfluidic
polymeric device. Biomimetic superhydrophobic surfaces were prepared on polystyrene …

Stretching fibroblasts remodels fibronectin and alters cancer cell migration

M Ao, BM Brewer, L Yang, OE Franco Coronel… - Scientific reports, 2015 - nature.com
Most investigations of cancer-stroma interactions have focused on biochemical signaling
effects, with much less attention being paid to biophysical factors. In this study, we …