Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in
vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts …

N6-methyladenosine (m6A) is a widely studied and abundant RNA modification. The m6A
mark regulates the fate of RNAs in various ways, which in turn drives changes in cell …

We present RBPNet, a novel deep learning method, which predicts CLIP-seq crosslink count
distribution from RNA sequence at single-nucleotide resolution. By training on up to a million …

KAR4, the yeast homolog of the mammalian mRNA N6A-methyltransferase complex
component METTL14, is required for two disparate developmental programs in …

Disordered regions within RNA binding proteins are required to control mRNA decay and
protein synthesis. To understand how these disordered regions modulate gene expression …

The covalent modification of RNA nucleotides is a powerful layer of post-transcriptional
control of gene expression across the tree of life. Historically, only abundant modifications …