Chiral stationary phases and applications in gas chromatography

G Betzenbichler, L Huber, S Kräh, MLK Morkos… - Chirality, 2022 - Wiley Online Library
Chiral compounds are ubiquitous in nature and play a pivotal role in biochemical processes,
in chiroptical materials and applications, and as chiral drugs. The analysis and …

Evolution of chiral stationary phase design in the Pirkle laboratories

CJ Welch - Journal of Chromatography A, 1994 - Elsevier
An historical review of the design of chiral stationary phases (CSPs) in the Pirkle
laboratories is presented. Beginning with the discovery of the non-equivalence of nuclear …

[LIVRE][B] Stereochemistry of organic compounds

EL Eliel, SH Wilen - 1994 - books.google.com
Stereochemistry of Organic Compounds The first fully referenced, comprehensive book on
this subject in more than thirty years, Stereochemistry of Organic Compounds contains up-to …

Considerations of chiral recognition relevant to the liquid chromatography separation of enantiomers

WH Pirkle, TC Pochapsky - Chemical Reviews, 1989 - ACS Publications
The dependence of the chemical or biological activity of a substance often depends upon its
stereochemistry, a fact recognized for over a century. However, accurate descriptions of the …

Resolution of enantiomeric aromatic alcohols on a cellulose tribenzoate high-performance liquid chromatography chiral stationary phase: a proposed chiral …

IW Wainer, RM Stiffin, T Shibata - Journal of chromatography A, 1987 - Elsevier
The study investigates the chiral recognition mechanism for the stereochemical resolution of
enantiomeric aromatic alcohols on a commercially available cellulose tribenzoate high …

A rational approach to the design of highly-effective chiral stationary phases

WH Pirkle, HH Myung, B Bank - Journal of Chromatography A, 1984 - Elsevier
Geometric considerations require that a minimum of three simultaneous interactions occur if
a chiral molecule is to “recognize” the chirality of other molecules. Moreover, chiral …

Preparative chromatographic separation of enantiomers

E Francotte, A Junker-Buchheit - Journal of Chromatography B: Biomedical …, 1992 - Elsevier
The potential of the chromatographic separation of enantiomers on a preparative scale as a
tool for the isolation of optically pure compounds is gaining increasing recognition. This …

Resolution of enantiomeric amides on a cellulose-based chiral stationary phase: Steric and electronic effects

IW Wainer, MC Alembik - Journal of Chromatography A, 1986 - Elsevier
A series of enantiomeric amides were resolve on a commercially available chiral stationary
phase (CSP0 consisting of cellulose tribenzoate coated on macroporous silica. The amides …

Chiral stationary phases based on small molecules: An update of the last 17 years

C Fernandes, YZ Phyo, AS Silva… - Separation & …, 2018 - Taylor & Francis
A literature survey covering the report on Pirkle-type chiral stationary phases (CSPs) from
January 2000 to March 2017 is presented in this review. More than 200 CSPs comprising …

Small molecules as chromatographic tools for HPLC enantiomeric resolution: Pirkle-type chiral stationary phases evolution

C Fernandes, ME Tiritan, M Pinto - Chromatographia, 2013 - Springer
This review focuses on the evolution of Pirkle-type chiral stationary phases (CSPs), based
on chiral recognition mechanism of small molecules and applications directly related with …