Highlights•Breakthrough in automatic neuron reconstruction from VEM data will enable the
reconstruction of much larger data sets in the future.•Volume electron microscopy imaging …

INTRODUCTION The brain of mammals consists of an enormously dense network of
neuronal wires: the axons and dendrites of nerve cells. Their packing density is so high that …

Neural circuits can be reconstructed from brain images acquired by serial section electron
microscopy. Image analysis has been performed by manual labor for half a century, and …

Reconstruction and annotation of volume electron microscopy data sets of brain tissue is
challenging but can reveal invaluable information about neuronal circuits. Significant …

Abstract 3D electron microscopy (EM) has been successful at map** invertebrate nervous
systems, but the approach has been limited to small chunks of mammalian brains. To scale …

Maps of the nervous system that identify individual cells along with their type, subcellular
components and connectivity have the potential to elucidate fundamental organizational …

The field of connectomics aims to reconstruct the wiring diagram of Neurons and synapses
to enable new insights into the workings of the brain. Reconstructing and analyzing the …

Pixel-accurate tracking of objects is a key element in many computer vision applications,
often solved by iterated individual object tracking or instance segmentation followed by …

We define and study error detection and correction tasks that are useful for 3D
reconstruction of neurons from electron microscopic imagery, and for image segmentation …

Most current state-of-the-art connectome reconstruction pipelines have two major steps:
initial pixel-based segmentation with affinity prediction and watershed transform, and refined …