Fatty acid synthase (FASN) as a therapeutic target in breast cancer
JA Menendez, R Lupu - Expert opinion on therapeutic targets, 2017 - Taylor & Francis
Introduction: Ten years ago, we put forward the metabolo-oncogenic nature of fatty acid
synthase (FASN) in breast cancer. Since the conception of this hypothesis, which provided a …
synthase (FASN) in breast cancer. Since the conception of this hypothesis, which provided a …
Molecular pathways: fatty acid synthase
SF Jones, JR Infante - Clinical Cancer Research, 2015 - AACR
Therapies that target tumor metabolism represent a new horizon in anticancer therapies. In
particular, cancer cells are dependent on the generation of lipids, which are essential for cell …
particular, cancer cells are dependent on the generation of lipids, which are essential for cell …
[HTML][HTML] Lipid metabolic reprogramming as an emerging mechanism of resistance to kinase inhibitors in breast cancer
Breast cancer is one of the leading causes of death in women in the United States. In
general, patients with breast cancer undergo surgical resection of the tumor and/or receive …
general, patients with breast cancer undergo surgical resection of the tumor and/or receive …
Lipid Metabolic Reprogramming: Implications in Development of Cancer Drug Resistance and Nonalcoholic Fatty Liver Disease
WW Feng - 2020 - search.proquest.com
Dysregulated lipid metabolism contributes to the development and progression of many
diseases. Breast cancer is the most common malignancy afflicting women worldwide. Breast …
diseases. Breast cancer is the most common malignancy afflicting women worldwide. Breast …