[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application

ME Ladd, P Bachert, M Meyerspeer, E Moser… - Progress in nuclear …, 2018 - Elsevier
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues

J Xu, JJ Chung, T ** - NMR in Biomedicine, 2023 - Wiley Online Library
Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …

Snapshot‐CEST: optimizing spiral‐centric‐reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T

M Zaiss, P Ehses, K Scheffler - NMR in Biomedicine, 2018 - Wiley Online Library
Gradient echo (GRE)‐based acquisition provides a robust readout method for chemical
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …

Non-invasive map** of brown adipose tissue activity with magnetic resonance imaging

Z Cai, Q Zhong, Y Feng, Q Wang, Z Zhang, C Wei… - Nature …, 2024 - nature.com
Thermogenic brown adipose tissue (BAT) has a positive impact on whole-body metabolism.
However, in vivo map** of BAT activity typically relies on techniques involving ionizing …

Creatine and phosphocreatine map** of mouse skeletal muscle by a polynomial and Lorentzian line‐shape fitting CEST method

L Chen, PB Barker, RG Weiss… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To obtain high‐resolution Cr and PCr maps of mouse skeletal muscle using a
polynomial and Lorentzian line‐shape fitting (PLOF) CEST method. Methods Wild‐type mice …

Validation of the presence of fast exchanging amine CEST effect at low saturation powers and its influence on the quantification of APT

C Sun, Y Zhao, Z Zu - Magnetic resonance in medicine, 2023 - Wiley Online Library
Purpose Accurately quantifying the amide proton transfer (APT) effect and the underlying
exchange parameters is crucial for its applications, but previous studies have reported …

Investigation of the contribution of total creatine to the CEST Z‐spectrum of brain using a knockout mouse model

L Chen, H Zeng, X Xu, NN Yadav, S Cai… - NMR in …, 2017 - Wiley Online Library
The current study aims to assign and estimate the total creatine (tCr) signal contribution to
the Z‐spectrum in mouse brain at 11.7 T. Creatine (Cr), phosphocreatine (PCr) and protein …

Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition

R Sui, L Chen, Y Li, J Huang, KWY Chan… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To develop a steady‐state saturation with radial readout chemical exchange
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …

Assignment of molecular origins of NOE signal at− 3.5 ppm in the brain

Y Zhao, C Sun, Z Zu - Magnetic resonance in medicine, 2023 - Wiley Online Library
Purpose Nuclear Overhauser enhancemen mediated saturation transfer effect, termed NOE
(− 3.5 ppm), is a major source of CEST MRI contrasts at 3.5 ppm in the brain. Previous …

Quantifying amide proton exchange rate and concentration in chemical exchange saturation transfer imaging of the human brain

HY Heo, Z Han, S Jiang, M Schär, PCM van Zijl, J Zhou - Neuroimage, 2019 - Elsevier
Current chemical exchange saturation transfer (CEST) neuroimaging protocols typically
acquire CEST-weighted images, and, as such, do not essentially provide quantitative proton …