Neuroimaging biomarkers for Alzheimer's disease

F Márquez, MA Yassa - Molecular neurodegeneration, 2019 - Springer
Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …

Early-life adversity and neurological disease: age-old questions and novel answers

AK Short, TZ Baram - Nature Reviews Neurology, 2019 - nature.com
Neurological illnesses, including cognitive impairment, memory decline and dementia, affect
over 50 million people worldwide, imposing a substantial burden on individuals and society …

Functional imbalance of anterolateral entorhinal cortex and hippocampal dentate/CA3 underlies age-related object pattern separation deficits

ZM Reagh, JA Noche, NJ Tustison, D Delisle… - Neuron, 2018 - cell.com
The entorhinal cortex (EC) is among the earliest brain areas to deteriorate in Alzheimer's
disease (AD). However, the extent to which functional properties of the EC are altered in the …

Neuroimaging hippocampal subfields in schizophrenia and bipolar disorder: a systematic review and meta-analysis

UK Haukvik, CK Tamnes, E Söderman… - Journal of psychiatric …, 2018 - Elsevier
The hippocampus is a complex structure consisting of subregions with specialized
cytoarchitecture and functions. Magnetic resonance imaging (MRI) studies in psychotic …

Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology

DH Adler, LEM Wisse, R Ittyerah… - Proceedings of the …, 2018 - National Acad Sciences
Although the hippocampus is one of the most studied structures in the human brain, limited
quantitative data exist on its 3D organization, anatomical variability, and effects of disease …

Integration and differentiation of hippocampal memory traces

IK Brunec, J Robin, RK Olsen, M Moscovitch… - Neuroscience & …, 2020 - Elsevier
Prevailing theories of hippocampal function argue that memories are rapidly encoded by
non-overlap** memory traces. Concurrently, the hippocampus has been argued to …

Exercise-induced neuroplasticity: Balance training increases cortical thickness in visual and vestibular cortical regions

AK Rogge, B Röder, A Zech, K Hötting - Neuroimage, 2018 - Elsevier
Physical exercise has been shown to induce structural plasticity in the human brain and to
enhance cognitive functions. While previous studies focused on aerobic exercise …

Hippocampal maturation drives memory from generalization to specificity

A Keresztes, CT Ngo, U Lindenberger… - Trends in Cognitive …, 2018 - cell.com
During early ontogeny, the rapid and cumulative acquisition of world knowledge contrasts
with slower improvements in the ability to lay down detailed and long-lasting episodic …

Age-related deficits in the mnemonic similarity task for objects and scenes

SM Stark, CEL Stark - Behavioural brain research, 2017 - Elsevier
Abstract Using the Mnemonic Similarity Task (MST), we have demonstrated an age-related
impairment in lure discrimination, or the ability to recognize an item as distinct from one that …

[HTML][HTML] A protocol for manual segmentation of medial temporal lobe subregions in 7 Tesla MRI

D Berron, P Vieweg, A Hochkeppler, JB Pluta… - NeuroImage: Clinical, 2017 - Elsevier
Recent advances in MRI and increasing knowledge on the characterization and anatomical
variability of medial temporal lobe (MTL) anatomy have paved the way for more specific …