Tissue response to neural implants: the use of model systems toward new design solutions of implantable microelectrodes
The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …
Flexible, penetrating brain probes enabled by advances in polymer microfabrication
A Weltman, J Yoo, E Meng - Micromachines, 2016 - mdpi.com
The acquisition of high-fidelity, long-term neural recordings in vivo is critically important to
advance neuroscience and brain–machine interfaces. For decades, rigid materials such as …
advance neuroscience and brain–machine interfaces. For decades, rigid materials such as …
Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo
Brain function depends on simultaneous electrical, chemical and mechanical signaling at
the cellular level. This multiplicity has confounded efforts to simultaneously measure or …
the cellular level. This multiplicity has confounded efforts to simultaneously measure or …
Mechanically-compliant intracortical implants reduce the neuroinflammatory response
Objective. The mechanisms underlying intracortical microelectrode encapsulation and
failure are not well understood. A leading hypothesis implicates the role of the mechanical …
failure are not well understood. A leading hypothesis implicates the role of the mechanical …
Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording
Penetrating intracortical electrode arrays that record brain activity longitudinally are powerful
tools for basic neuroscience research and emerging clinical applications. However …
tools for basic neuroscience research and emerging clinical applications. However …
Relationship between intracortical electrode design and chronic recording function
Intracortical electrodes record neural signals directly from local populations of neurons in the
brain, and conduct them to external electronics that control prosthetics. However, the …
brain, and conduct them to external electronics that control prosthetics. However, the …
Explant analysis of Utah electrode arrays implanted in human cortex for brain-computer-interfaces
Brain-computer interfaces are being developed to restore movement for people living with
paralysis due to injury or disease. Although the therapeutic potential is great, long-term …
paralysis due to injury or disease. Although the therapeutic potential is great, long-term …
Single-trial decoding of movement intentions using functional ultrasound neuroimaging
New technologies are key to understanding the dynamic activity of neural circuits and
systems in the brain. Here, we show that a minimally invasive approach based on …
systems in the brain. Here, we show that a minimally invasive approach based on …
Mechanical and biological interactions of implants with the brain and their impact on implant design
D Prodanov, J Delbeke - Frontiers in neuroscience, 2016 - frontiersin.org
Neural prostheses have already a long history and yet the cochlear implant remains the only
success story about a longterm sensory function restoration. On the other hand, neural …
success story about a longterm sensory function restoration. On the other hand, neural …
Nanoporous gold as a neural interface coating: effects of topography, surface chemistry, and feature size
CAR Chapman, H Chen, M Stamou… - … applied materials & …, 2015 - ACS Publications
Designing neural interfaces that maintain close physical coupling of neurons to an electrode
surface remains a major challenge for both implantable and in vitro neural recording …
surface remains a major challenge for both implantable and in vitro neural recording …