Abstract Spilanthol (C14H23NO, 221.339 g/mol) is a bioactive compound that is found in
many different plants that are used as traditional remedies throughout the world. It is present …

Interest in alkylamide, as a class of compound, has grown tremendously in recent years.
This interest is due to the many presumed benefits in food, cosmetics, and medicine. This …

Despite advances in medicine and numerous agents that counteract pain, millions of
patients continue to suffer. Attention has been given to identify novel botanical interventions …

Alkamides are natural products formed by connecting straight-chain, mostly unsaturated,
aliphatic acids with various amines by an amide linkage. More than 300 derivatives are …

Several species of Spilanthes, commonly known as the 'toothache'plants, are widely used by
different communities as food ingredient in their traditional cuisines. Different parts of these …

The consumption of medicinal plants has notably increased over the past two decades.
People consider herbal products as safe because of their natural origin, without taking into …

Purpose To evaluate the efficacy of a new food-grade lecithin formulation of standardized
extracts of Zingiber officinale and Acmella oleracea on pain and inflammation. Patients and …

Alkamides are a group of bioactive natural compounds showing broad structural variability
and an important range of biological activities, such as immunomodulatory, antimicrobial …

Background Spilanthol is a bioactive alkamide widespread in Asteraceae and Piperaceae
plant species. The species from Asteraceae are famous because of their sensorial …

Heliopsis longipes roots have been widely used in Mexican traditional medicine to relieve
pain, mainly, toothaches. Previous studies have shown that affinin, the major alkamide of …