A growing body of evidence points to CodY, a global regulator in Gram-positive bacteria, as
a critical link between microbial physiology and pathogenesis in diverse environments …

The guanosine-based second messengers (p) ppGpp and c-di-GMP are key players of the
physiological regulation of the Gram-positive model organism Bacillus subtilis. Their …

In eukaryotes, RNA species originating from pervasive transcription are regulators of various
cellular processes, from the expression of individual genes to the control of cellular …

The nutritional alarmones ppGpp and pppGpp (collectively:(p) ppGpp) are nucleotide-based
second messengers enabling bacteria to respond to environmental and stress conditions …

Resistance to diverse antibiotics can result from mutations in RNA polymerase (RNAP), but
the underlying mechanisms remain poorly understood. In this study, we compare two …

Staphylococcus aureus (S. aureus), as the main pathogen in milk and dairy products,
usually causes intoxication with vomiting and various kinds of inflammation after entering the …

Transcription termination factor Rho is known for its ubiquitous role in suppression of
pervasive, mostly antisense, transcription. In the model Gram-positive bacterium Bacillus …

Highlights•M w in media with different PTS-sugars were larger than in the medium with
glycerol.•CodY seems to be activated in the cells cultivated in the media with PTS …

The Hsp100/Clp protease complexes of Bacillus subtilis ClpXP and ClpCP are involved in
the control of many interconnected developmental and stress response regulatory networks …

Many bacteria utilize actin-like proteins to direct peptidoglycan (PG) synthesis. MreB and
MreB-like proteins are thought to act as scaffolds, guiding the localization and activity of key …