New psychoactive substances: a review and updates

A Shafi, AJ Berry, H Sumnall… - Therapeutic …, 2020 - journals.sagepub.com
New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms

P Zanos, R Moaddel, PJ Morris, LM Riggs… - Pharmacological …, 2018 - Elsevier
Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …

Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

Advantages and limitations of animal schizophrenia models

M Białoń, A Wąsik - International Journal of Molecular Sciences, 2022 - mdpi.com
Mental illness modeling is still a major challenge for scientists. Animal models of
schizophrenia are essential to gain a better understanding of the disease etiopathology and …

Reports of adverse events associated with use of novel psychoactive substances, 2013–2016: a review

BK Logan, ALA Mohr, M Friscia… - Journal of Analytical …, 2017 - academic.oup.com
Novel psychoactive substances (NPS) represent significant analytical and interpretive
challenges to forensic and clinical toxicologists. Timely access to case reports and reports of …

New/emerging psychoactive substances and associated psychopathological consequences

F Schifano, F Napoletano, S Chiappini… - Psychological …, 2021 - cambridge.org
BackgroundThe present paper provides an updated review of both the large number of
new/novel/emerging psychoactive substances (NPS) and their associated …

Tertiary amine synthesis via reductive coupling of amides with Grignard reagents

LG **e, DJ Dixon - Chemical Science, 2017 - pubs.rsc.org
A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary
amides affording functionalised tertiary amine products via an efficient and technically …

Reports of adverse events associated with use of novel psychoactive substances, 2017–2020: a review

ALA Mohr, BK Logan, MF Fogarty… - Journal of Analytical …, 2022 - academic.oup.com
An important role of modern forensic and clinical toxicologists is to monitor the adverse
events of novel psychoactive substances (NPS). Following a prior review from 2013 to 2016 …

New psychoactive substances (NPS) and serotonin syndrome onset: A systematic review

F Schifano, S Chiappini, A Miuli, JM Corkery… - Experimental …, 2021 - Elsevier
The use of several new psychoactive substances (NPS) has become very popular and is
posing global health risks. Chemically and pharmacologically diverse molecules are …

Prefrontal and hippocampal parvalbumin interneurons in animal models for schizophrenia: a systematic review and meta-analysis

T Santos-Silva, D dos Santos Fabris… - Schizophrenia …, 2024 - academic.oup.com
Background Consistent with postmortem findings in patients, most animal models for
schizophrenia (SCZ) present abnormal levels of parvalbumin (PV), a marker of fast-spiking …