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Glioblastoma therapy: Past, present and future
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
Applications of focused ultrasound-mediated blood-brain barrier opening
The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
Ultrasound-mediated blood–brain barrier opening: An effective drug delivery system for theranostics of brain diseases
Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Biomimetic nanosonosensitizers combined with noninvasive ultrasound actuation to reverse drug resistance and sonodynamic-enhanced chemotherapy against …
H Chen, S Zhang, Q Fang, H He, J Ren, D Sun, J Lai… - ACS …, 2022 - ACS Publications
Glioblastoma (GBM) is the most devastating brain tumor and highly resistant to conventional
chemotherapy. Herein, we introduce biomimetic nanosonosensitizer systems (MDNPs) …
chemotherapy. Herein, we introduce biomimetic nanosonosensitizer systems (MDNPs) …
Strategies to improve drug delivery across the blood–brain barrier for glioblastoma
Abstract Purpose of Review Glioblastoma remains resistant to most conventional treatments.
Despite scientific advances in the past three decades, there has been a dearth of effective …
Despite scientific advances in the past three decades, there has been a dearth of effective …
Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound
Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
[HTML][HTML] Applications of focused ultrasound for the treatment of glioblastoma: a new frontier
Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …
[HTML][HTML] Advancements in glioma care: Focus on emerging neurosurgical techniques
Background: Despite significant advances in understanding the molecular pathways of
glioma, translating this knowledge into effective long-term solutions remains a challenge …
glioma, translating this knowledge into effective long-term solutions remains a challenge …
[HTML][HTML] Obstacles to glioblastoma treatment two decades after temozolomide
Simple Summary Glioblastomas are the most common and aggressive brain tumors in
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …
[HTML][HTML] Barrier-breaking effects of ultrasonic cavitation for drug delivery and biomarker release
Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …
bidirectional channels on biological barriers for both intratumoral drug delivery and …