The incidence of microbial infections in orthopedic prosthetic surgeries is a perennial
problem that increases morbidity and mortality, representing one of the major complications …

As an endogenous signaling molecule, metal ions not only play an important role in the
physiological development of the maxillofacial bone, but also can improve the repair of …

Implant‐associated osteomyelitis (IAOM) is characterized by bone infection and destruction;
current therapy of antibiotic treatment and surgical debridement often results in drug …

Implant-associated infections frequently complicate orthopedic surgeries, resulting in
challenging issues. The current therapy of antibiotic treatment and surgical debridement …

Infected bone defect repair has long been a major challenge in orthopedic surgery. Apart
from bacterial contamination, excessive generation of reactive oxygen species (ROS), and …

Bone is a complex organic–inorganic composite tissue composed of∼ 30% organics and∼
70% hydroxyapatite (HAp). Inspired by this, we used 30% collagen and 70% HAp extracted …

Purpose During treatment of infected bone defects, control of infection is necessary for
effective bone repair, and hence controlled topical application of antibiotics is required in …

Herein, we introduce a novel composite hydrogel scaffold designed for addressing
infectious jaw defects, a significant challenge in clinical settings caused by the inherent …

In recent years, the prevalence of bone diseases is showing an increasing trend, which is
mainly attributed to the aging of the global population. However, bone repair and …

Construction of organic–inorganic composites similar to natural bone in terms of structure
and composition has attracted extensive attention. However, the clinical applications of …