The regulation of RNA modification systems: the next frontier in epitranscriptomics?
MR Schaefer - Genes, 2021 - mdpi.com
RNA modifications, long considered to be molecular curiosities embellishing just abundant
and non-coding RNAs, have now moved into the focus of both academic and applied …
and non-coding RNAs, have now moved into the focus of both academic and applied …
A brief review of machine learning methods for RNA methylation sites prediction
H Wang, S Wang, Y Zhang, S Bi, X Zhu - Methods, 2022 - Elsevier
Thanks to the tremendous advancement of deep sequencing and large-scale profiling,
epitranscriptomics has become a rapidly growing field. As one of the most important parts of …
epitranscriptomics has become a rapidly growing field. As one of the most important parts of …
A hybrid residue based sequential encoding mechanism with XGBoost improved ensemble model for identifying 5-hydroxymethylcytosine modifications
RNA modifications play an important role in actively controlling recently created formation in
cellular regulation mechanisms, which link them to gene expression and protein. The RNA …
cellular regulation mechanisms, which link them to gene expression and protein. The RNA …
Weakly supervised learning of RNA modifications from low-resolution epitranscriptome data
Motivation Increasing evidence suggests that post-transcriptional ribonucleic acid (RNA)
modifications regulate essential biomolecular functions and are related to the pathogenesis …
modifications regulate essential biomolecular functions and are related to the pathogenesis …
[HTML][HTML] Machine learning applications in RNA modification sites prediction
Ribonucleic acid (RNA) modifications are post-transcriptional chemical composition
changes that have a fundamental role in regulating the main aspect of RNA function …
changes that have a fundamental role in regulating the main aspect of RNA function …
CNN6mA: Interpretable neural network model based on position-specific CNN and cross-interactive network for 6mA site prediction
Abstract N6-methyladenine (6mA) plays a critical role in various epigenetic processing
including DNA replication, DNA repair, silencing, transcription, and diseases such as …
including DNA replication, DNA repair, silencing, transcription, and diseases such as …
Dynamic regulation and key roles of ribonucleic acid methylation
J Zou, H Liu, W Tan, Y Chen, J Dong, S Bai… - Frontiers in Cellular …, 2022 - frontiersin.org
Ribonucleic acid (RNA) methylation is the most abundant modification in biological systems,
accounting for 60% of all RNA modifications, and affects multiple aspects of RNA (including …
accounting for 60% of all RNA modifications, and affects multiple aspects of RNA (including …
Emerging Role of Environmental Epitranscriptomics and RNA Modifications in Parkinson's Disease
JT Gionco, AI Bernstein - Journal of Parkinson's disease, 2024 - content.iospress.com
Environmental risk factors and gene-environment interactions play a critical role in
Parkinson's disease (PD). However, the relatively large contribution of environmental risk …
Parkinson's disease (PD). However, the relatively large contribution of environmental risk …
Sequence based model using deep neural network and hybrid features for identification of 5-hydroxymethylcytosine modification
RNA modifications are pivotal in the development of newly synthesized structures,
showcasing a vast array of alterations across various RNA classes. Among these, 5 …
showcasing a vast array of alterations across various RNA classes. Among these, 5 …
i5hmCVec: Identifying 5-Hydroxymethylcytosine Sites of Drosophila RNA Using Sequence Feature Embeddings
HY Liu, PF Du - Frontiers in Genetics, 2022 - frontiersin.org
5-Hydroxymethylcytosine (5hmC), one of the most important RNA modifications, plays an
important role in many biological processes. Accurately identifying RNA modification sites …
important role in many biological processes. Accurately identifying RNA modification sites …