Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence

AK Bonkhoff, C Grefkes - Brain, 2022 - academic.oup.com
Stroke ranks among the leading causes for morbidity and mortality worldwide. New and
continuously improving treatment options such as thrombolysis and thrombectomy have …

[HTML][HTML] Integrative approaches in acute ischemic stroke: from symptom recognition to future innovations

VM Saceleanu, C Toader, H Ples… - Biomedicines, 2023 - mdpi.com
Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke
stands out, representing a significant worldwide health issue with important socio-economic …

Leveraging factors of self-efficacy and motivation to optimize stroke recovery

R Gangwani, A Cain, A Collins, JM Cassidy - Frontiers in Neurology, 2022 - frontiersin.org
The International Classification of Functioning, Disability and Health framework recognizes
that an individual's functioning post-stroke reflects an interaction between their health …

Neural stem cell-derived exosomes-loaded adhesive hydrogel controlled-release promotes cerebral angiogenesis and neurological function in ischemic stroke

C Gu, Y Li, J Liu, S Liu, J Long, Q Zhang, W Duan… - Experimental …, 2023 - Elsevier
Objective Ischemic stroke has become one of the leading diseases for international death,
which brings burden to the economy and society. Exosomes (Exos) derived following neural …

Restoring after central nervous system injuries: neural mechanisms and translational applications of motor recovery

Z Gao, Z Pang, Y Chen, G Lei, S Zhu, G Li, Y Shen… - Neuroscience …, 2022 - Springer
Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal
cord injury, are leading causes of long-term disability. It is estimated that more than half of …

Abnormal dynamic functional connectivity is linked to recovery after acute ischemic stroke

AK Bonkhoff, MD Schirmer, M Bretzner… - Human brain …, 2021 - Wiley Online Library
The aim of the current study was to explore the whole‐brain dynamic functional connectivity
patterns in acute ischemic stroke (AIS) patients and their relation to short and long‐term …

Modulation of neural co-firing to enhance network transmission and improve motor function after stroke

K Ganguly, P Khanna, RJ Morecraft, DJ Lin - Neuron, 2022 - cell.com
Stroke is a leading cause of disability. While neurotechnology has shown promise for
improving upper limb recovery after stroke, efficacy in clinical trials has been variable. Our …

Poststroke arm and hand paresis: should we target the cervical spinal cord?

E Pirondini, E Carranza, JM Balaguer, E Sorensen… - Trends in …, 2022 - cell.com
Despite advances in understanding of corticospinal motor control and stroke
pathophysiology, current rehabilitation therapies for poststroke upper limb paresis have …

Corticospinal fibers with different origins impact motor outcome and brain after subcortical stroke

J Liu, C Wang, W Qin, H Ding, J Guo, T Han, J Cheng… - Stroke, 2020 - ahajournals.org
Background and Purpose: Motor deficit is the most common disability after stroke, and early
prediction of motor outcome is critical for early interventions. Here, we constructed a fine …

Extracellular vesicles from medicated plasma of Buyang Huanwu decoction-preconditioned neural stem cells accelerate neurological recovery following ischemic …

J Long, C Gu, Q Zhang, J Liu, J Huang, Y Li… - Frontiers in cell and …, 2023 - frontiersin.org
Introduction: The neurological impairment of survivors after ischemic stroke poses a serious
risk to their quality of life and health. Effective therapeutic options are still lacking. Neural …