Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri

A Sarfraz, TU Wara, Sheheryar, K Chen… - Frontiers in …, 2023‏ - frontiersin.org
Primary Amoebic Meningoencephalitis (PAM), a severe lethal brain disease, is caused by a
parasite, Naegleria fowleri, also known as the “brain-eating amoeba”. The chances of a …

Decrypting the multi-genome data for chimeric vaccine designing against the antibiotic resistant Yersinia pestis

A Sarfraz, SQUA Fatima, M Shehroz, I Ahmad… - International …, 2024‏ - Elsevier
Yersinia pestis, the causative agent of plague, is a gram-negative bacterium that can be fatal
if not treated properly. Three types of plague are currently known: bubonic, septicemic, and …

Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach

M Shah, F Sitara, A Sarfraz, M Shehroz… - Frontiers in …, 2024‏ - frontiersin.org
Opisthorchis viverrini is the etiological agent of the disease opisthorchiasis and related
cholangiocarcinoma (CCA). It infects fish-eating mammals and more than 10 million people …

Genome-wide characterization leading to simple sequence repeat (SSR) markers development in Shorea robusta

G Mishra, RK Meena, R Kant, S Pandey… - Functional & Integrative …, 2023‏ - Springer
Abstract Tropical rainforests in Southeast Asia are enriched by multifarious biota dominated
by Dipterocarpaceae. In this family, Shorea robusta is an ecologically sensitive and …

[HTML][HTML] mRNA vaccine designing using chikungunya virus E glycoprotein through immunoinformatics-guided approaches

S Jaan, A Zaman, S Ahmed, M Shah, SC Ojha - Vaccines, 2022‏ - mdpi.com
Chikungunya virus is an alphavirus transmitted by mosquitos that develops into
chikungunya fever and joint pain in humans. This virus' name originated from a Makonde …

Computer-aided genomic data analysis of drug-resistant Neisseria gonorrhoeae for the Identification of alternative therapeutic targets

A Qasim, S Jaan, TU Wara, M Shehroz… - Frontiers in Cellular …, 2023‏ - frontiersin.org
Neisseria gonorrhoeae is an emerging multidrug resistance pathogen that causes sexually
transmitted infections in men and women. The N. gonorrhoeae has demonstrated an …

Proteome level analysis of drug-resistant Prevotella melaninogenica for the identification of novel therapeutic candidates

M Shah, A Anwar, A Qasim, S Jaan, A Sarfraz… - Frontiers in …, 2023‏ - frontiersin.org
The management of infectious diseases has become more critical due to the development of
novel pathogenic strains with enhanced resistance. Prevotella melaninogenica, a gram …

Chlamydia trachomatis core genome data mining for promising novel drug targets and chimeric vaccine candidates identification

M Aslam, M Shehroz, F Ali, A Zia, S Pervaiz… - Computers in Biology …, 2021‏ - Elsevier
Chlamydia trachomatis is involved in most sexually transmitted diseases. The species has
emerged as a major public health threat due to its multidrug-resistant capabilities, and new …

Multi-epitope chimeric vaccine designing and novel drug targets prioritization against multi-drug resistant Staphylococcus pseudintermedius

S Jaan, M Shah, N Ullah, A Amjad, MS Javed… - Frontiers in …, 2022‏ - frontiersin.org
Biofilm synthesizing multi-drug resistant Staphylococcus pseudintermedius bacteria has
been recognized as the human infectious agent. It has been detected in the diseases of skin …

Genome skimming-based simple sequence repeat (SSR) marker discovery and characterization in Grevillea robusta

A Dabral, A Shamoon, RK Meena, R Kant… - … and Molecular Biology …, 2021‏ - Springer
Proteaceae, a largely southern hemisphere family consisting of 80 genera distributed in
Australia and southern Africa as its centres of greatest diversity, also extends well in …