The discovery of myostatin and our introduction to the “Mighty Mouse” over a decade ago
spurred both basic and applied research and impacted popular culture as well. The …

Myostatin (MSTN) is one of the key factors regulating myogenesis. Because of its role as a
negative regulator of muscle mass deposition, much interest has been given to its protein …

The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle
growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the …

1. Introduction 2. A Conceptual Framework for Growth 2.1. The Dynamic Energy Budget
(DEB) Model for Growth 2.2. Myocyte Growth 3. Stress Effect on Energy Available for Growth …

Simple Summary Gilthead seabream (Sparus aurata) is a teleost fish of great relevance in
marine aquaculture, especially in the Mediterranean area and one of the most important …

In the last decade, myostatin (MSTN), a member of the TGFβ superfamily, has emerged as a
strong inhibitor of muscle growth in mammals. In fish many studies reveal a strong …

Control of tissue metabolism and growth involves interactions between organs, tissues, and
cell types, mediated by cytokines or direct communication through cellular exchanges …

1 MYOSTATIN INHIBITS MYOSATELLITE CELL PROLIFERATION AND CONSEQUENTLY 1
ACTIVATES DIFFERENTIATION: EVIDENCE FOR ENDOCRINE-REGUL Page 1 1 …

Interactions between tissues and cell types, mediated by cytokines or direct cell–cell
exchanges, regulate growth. To determine whether mature adipocytes influence the in vitro …

Although myostatin negatively regulates skeletal muscle growth, its function in heart is
virtually unknown. Herein we demonstrate that it inhibits basal and IGF‐stimulated …