Breast cancer is characterized by considerable metabolic diversity. A relatively high
percentage of patients diagnosed with breast carcinoma do not respond to standard-of-care …

Oxylipins are potent biological mediators requiring strict control, but how they are removed
en masse during infection and inflammation is unknown. Here we show that …

Murine hepatitis virus strain A59 (MHV-A59) was shown to induce pyroptosis, apoptosis, and
necroptosis of infected cells, especially in the murine macrophages. However, whether …

Background Alcohol consumption has been shown to disrupt hepatic lipid homeostasis.
Long-chain acyl-CoA synthetase 1 (ACSL1) critically regulates hepatic fatty acid metabolism …

There exists a positive correlation between the unsaturated fatty acids (UFA) content in the
bovine species and their taste and nutritional significance. Long-chain acyl-CoA synthetase …

Regulatory T (T reg) cells are critical for immunological tolerance and immune homeostasis.
T reg cells strongly rely on mitochondrial metabolism and show a lower level of glycolysis …

Multiple types of regulated cell death (RCD) have been demonstrated to cause gut barrier
dysfunction in necrotizing enterocolitis (NEC); however, whether and how ferroptosis is …

Urinary tract infections (UTIs) are a common cause of sepsis worldwide. Annually, more than
60,000 US deaths can be attributed to sepsis secondary to UTIs, and African American/Black …

Background Covid-19 morbidity and mortality are associated with a dysregulated immune
response. Tools are needed to enhance existing immune profiling capabilities in affected …

Background The close relationship between ankylosing spondylitis (AS) and inflammatory
bowel diseases (IBD) has been supported by many aspects, including but not limited to …