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The validity of animal models of predisposition to depression
P Willner, PJ Mitchell - Behavioural pharmacology, 2002 - journals.lww.com
Some animal models of depression, including the majority of the more recently introduced
models, are better characterized as models of predisposition to depression. In the first part of …
models, are better characterized as models of predisposition to depression. In the first part of …
New perspectives on the neurodevelopmental effects of SSRIs
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for the treatment of
depression and anxiety-related disorders. These drugs target the serotonin transporter (5 …
depression and anxiety-related disorders. These drugs target the serotonin transporter (5 …
Of rodents and humans: A comparative review of the neurobehavioral effects of early life SSRI exposure in preclinical and clinical research
ME Glover, SM Clinton - International Journal of Developmental …, 2016 - Elsevier
Selective serotonin reuptake inhibitors (SSRIs) have been a mainstay pharmacological
treatment for women experiencing depression during pregnancy and postpartum for the past …
treatment for women experiencing depression during pregnancy and postpartum for the past …
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring
JDA Olivier, A Vallès, F van Heesch… - …, 2011 - Springer
Abstract Rationale Fluoxetine (Prozac®) is the most frequently prescribed drug to battle
depression in pregnant women, but its safety in the unborn child has not yet been …
depression in pregnant women, but its safety in the unborn child has not yet been …
The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring
JDA Olivier, H Åkerud, H Kaihola… - Frontiers in cellular …, 2013 - frontiersin.org
It has been estimated that 20% of pregnant women suffer from depression and it is well-
documented that maternal depression can have long-lasting effects on the child. Currently …
documented that maternal depression can have long-lasting effects on the child. Currently …
Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs)
The serotonin transporter gene (SLC6A4; synonyms, SERT, 5-HTT) is expressed much more
broadly during development than in adulthood. To obtain a full picture of all sites of SERT …
broadly during development than in adulthood. To obtain a full picture of all sites of SERT …
The neurodevelopmental effects of serotonin: a behavioural perspective
LJ Kepser, JR Homberg - Behavioural brain research, 2015 - Elsevier
Serotonin is well known for its role in psychiatric disorders like depression and autism, but it
is less clear how aberrant behaviour associated with these disorders are shaped by …
is less clear how aberrant behaviour associated with these disorders are shaped by …
The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: A review
The selective serotonin reuptake inhibitor (SSRI) Prozac®(fluoxetine) is widely prescribed
for the treatment of depression and anxiety-related disorders. While extensive research has …
for the treatment of depression and anxiety-related disorders. While extensive research has …
The effect of increased serotonergic neurotransmission on aggression: a critical meta-analytical review of preclinical studies
Rationale The role of serotonin (5-HT) on aggression has been extensively studied;
nonetheless, the role of this neurotransmitter in aggression is still inconclusive. Objectives …
nonetheless, the role of this neurotransmitter in aggression is still inconclusive. Objectives …
Delayed physical and neurobehavioral development and increased aggressive and depression-like behaviors in the rat offspring of dams fed a high-fat diet
CÁ Giriko, CA Andreoli, LV Mennitti… - International journal of …, 2013 - Elsevier
Early maternal exposure to a high-fat diet (HFD) may influence the brain development of rat
offspring and consequently affect physiology and behavior. Thus, in the present study, we …
offspring and consequently affect physiology and behavior. Thus, in the present study, we …