Progressive inflammation‐mediated neurodegeneration after traumatic brain or spinal cord injury
Traumatic brain injury (TBI) has been linked to dementia and chronic neurodegeneration.
Described initially in boxers and currently recognized across high contact sports, the …
Described initially in boxers and currently recognized across high contact sports, the …
Extracellular vesicles as an emerging frontier in spinal cord injury pathobiology and therapy
Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
[HTML][HTML] Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in …
Neuropsychological deficits, including impairments in learning and memory, occur after
spinal cord injury (SCI). In experimental SCI models, we and others have reported that such …
spinal cord injury (SCI). In experimental SCI models, we and others have reported that such …
Spinal cord injury-induced cognitive impairment: A narrative review
OV Alcántar-Garibay… - Neural Regeneration …, 2022 - journals.lww.com
Spinal cord injury is a serious damage to the spinal cord that can lead to life-long disability.
Based on its etiology, spinal cord injury can be classified as traumatic or non-traumatic …
Based on its etiology, spinal cord injury can be classified as traumatic or non-traumatic …
[HTML][HTML] Neuropathic pain after spinal cord injury: challenges and research perspectives
R Shiao, CA Lee-Kubli - Neurotherapeutics, 2018 - Elsevier
Neuropathic pain is a debilitating consequence of spinal cord injury (SCI) that remains
difficult to treat because underlying mechanisms are not yet fully understood. In part, this is …
difficult to treat because underlying mechanisms are not yet fully understood. In part, this is …
Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationship
X Sun, ZB Jones, X Chen, L Zhou, KF So… - Journal of …, 2016 - Springer
Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
[HTML][HTML] Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential
Extracellular vesicles (EVs) have been implicated mechanistically in the pathobiology of
neurodegenerative disorders, including central nervous system injury. However, the role of …
neurodegenerative disorders, including central nervous system injury. However, the role of …
Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death
Autophagy is a catabolic mechanism facilitating degradation of cytoplasmic proteins and
organelles in a lysosome-dependent manner. Autophagy flux is necessary for normal …
organelles in a lysosome-dependent manner. Autophagy flux is necessary for normal …
Cognitive impairment and mood states after spinal cord injury
Spinal cord injury (SCI) is believed to be associated with high rates of cognitive impairment,
which can result in complications in recovery. This study concerned two groups of adults …
which can result in complications in recovery. This study concerned two groups of adults …
Dementia, depression, and associated brain inflammatory mechanisms after spinal cord injury
Evaluation of the chronic effects of spinal cord injury (SCI) has long focused on sensorimotor
deficits, neuropathic pain, bladder/bowel dysfunction, loss of sexual function, and emotional …
deficits, neuropathic pain, bladder/bowel dysfunction, loss of sexual function, and emotional …