Advanced methods and novel biomarkers in autoimmune diseases‑a review of the recent years progress in systemic lupus erythematosus

KA Fenton, HL Pedersen - Frontiers in Medicine, 2023 - frontiersin.org
There are several autoimmune and rheumatic diseases affecting different organs of the
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …

The role of dendritic cells and their immunometabolism in rheumatoid arthritis

Y Suwa, Y Nagafuchi, S Yamada, K Fujio - Frontiers in Immunology, 2023 - frontiersin.org
Dendritic cells (DCs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA), a
prototypic autoimmune disease characterized by chronic synovitis and joint destruction …

The Notch signaling-regulated angiogenesis in rheumatoid arthritis: pathogenic mechanisms and therapeutic potentials

F Zhao, Y He, Z Zhao, J He, H Huang, K Ai… - Frontiers in …, 2023 - frontiersin.org
Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Co-delivery of aceclofenac and methotrexate nanoparticles presents an effective treatment for rheumatoid arthritis

S Negi, N Tandel, NK Garg, P Sharma… - International Journal …, 2024 - Taylor & Francis
Background Rheumatoid arthritis (RA) is a common acute inflammatory autoimmune
connective tissue arthropathy. The genetic studies, tissue analyses, experimental animal …

Role of IFN-α in Rheumatoid Arthritis

CMA Lin, JD Isaacs, FAH Cooles - Current Rheumatology Reports, 2024 - Springer
Abstract Purpose of Review Type 1 interferons (IFN-I) are of increasing interest across a
wide range of autoimmune rheumatic diseases. Historically, research into their role in …

[HTML][HTML] Rheumatoid arthritis has won the battle but not the war: How many joints will we save tomorrow?

VV Oberemok, O Andreeva, K Laikova, E Alieva… - Medicina, 2023 - mdpi.com
Rheumatoid arthritis refers to joint diseases of unclear etiology whose final stages can lead
to unbearable pain and complete immobility of the affected joints. As one of the most widely …

[HTML][HTML] Targeted Therapy of Antibody-Induced Autoimmune Arthritis Using Peptide-Guided Nanoparticles

H Nanjaiah, KD Moudgil - International Journal of Molecular Sciences, 2024 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
of the joints and it affects over 18 million people worldwide. Despite the availability of a …

Advances and applications in single-cell and spatial genomics

J Wang, F Ye, H Chai, Y Jiang, T Wang, X Ran… - Science China Life …, 2024 - Springer
The applications of single-cell and spatial technologies in recent times have revolutionized
the present understanding of cellular states and the cellular heterogeneity inherent in …

Inverse‐Vaccines for Rheumatoid Arthritis Re‐establish Metabolic and Immunological Homeostasis in Joint Tissues

A Thumsi, D Martínez, SJ Swaminathan… - Advanced …, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) causes immunological and metabolic imbalances in tissue,
exacerbating inflammation in affected joints. Changes in immunological and metabolic …

Current immunotherapy strategies for rheumatoid arthritis: The immunoengineering and delivery systems

C Zhang, P Ma, A Qin, L Wang, K Dai, Y Liu, J Zhao… - Research, 2023 - spj.science.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease accompanied by
persistent multiarticular synovitis and cartilage degradation. The present clinical treatments …