The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament
initially characterized in neural stem cells. However, current extensive evidence obtained in …

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and
progenitor cells. Clinically, it is associated with the selection and enrichment of …

The skin is the largest organ of the body and has an array of functions. Skin compartments,
epidermis, and hair follicles house stem cells that are indispensable for skin homeostasis …

The utility of induced pluripotent stem (iPS) cells for investigating the molecular logic of
pluripotency and for eventual clinical application is limited by the low efficiency of current …

The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work
of Yamanaka and Takahashi. From this point, fibroblasts are the most commonly used …

Hair greying (canities) is one of the earliest, most visible ageing‐associated phenomena,
whose modulation by genetic, psychoemotional, oxidative, senescence‐associated …

Putative epithelial stem cells were identified in the hair follicle bulge as quiescent “label
retaining cells”. The study of these cells was hindered until the identification of bulge cell …

Naturally fluorescent proteins have revolutionized biology by enabling what was formerly
invisible to be seen clearly. These proteins have allowed us to visualize, in real time …

The mammalian hair follicle represents a unique, highly regenerative neuroectodermal-
mesodermal interaction system that contains numerous stem cells. It is the only organ in the …

The ease of generating induced pluripotent stem (iPS) cells, and possibly their properties
after reprogramming, depends on the origin of the somatic cell starting population …