Supercritical fluid technology: an emphasis on drug delivery and related biomedical applications

RK Kankala, YS Zhang, SB Wang… - Advanced …, 2017‏ - Wiley Online Library
During the past few decades, supercritical fluid (SCF) has emerged as an effective
alternative for many traditional pharmaceutical manufacturing processes. Operating active …

Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals–a comprehensive review

L Padrela, MA Rodrigues, A Duarte, AMA Dias… - Advanced drug delivery …, 2018‏ - Elsevier
Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Preparation, characterization, and in vitro release investigation of lutein/zein nanoparticles via solution enhanced dispersion by supercritical fluids

D Hu, C Lin, L Liu, S Li, Y Zhao - Journal of food engineering, 2012‏ - Elsevier
Solution enhanced dispersion by supercritical fluids (SEDS) was applied for the production
of lutein/zein nanoparticles. The effects of the process variables on the morphology, drug …

Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications

N Tahir, A Madni, V Balasubramanian… - International journal of …, 2017‏ - Elsevier
Lipid-polymer hybrid nanoparticles (LPHNPs) are emerging platforms for drug delivery
applications. In the present study, methotrexate loaded LPHNPs consisted of PLGA and …

Poly (lactide-co-glycolide)-based micro and nanoparticles for the controlled drug delivery of vitamins

M Stevanovic, D Uskokovic - Current Nanoscience, 2009‏ - ingentaconnect.com
Controlled drug delivery systems and polymeric carriers have undergone significant
development in recent years. Polymers like polylactides (PLA), polyglycolides (PGA), poly …

A review of silk fibroin-based drug delivery systems and their applications

RH Yadav, M Kenchegowda, M Angolkar… - European Polymer …, 2024‏ - Elsevier
Silk proteins are highly versatile materials known for their exceptional biodegradability and
biocompatibility, making them valuable for diverse applications across various sectors …

Processing of materials for regenerative medicine using supercritical fluid technology

CA Garcia-Gonzalez, A Concheiro… - Bioconjugate …, 2015‏ - ACS Publications
The increase in the world demand of bone and cartilage replacement therapies urges the
development of advanced synthetic scaffolds for regenerative purposes, not only providing …

PLA/PLGA-Based Drug Delivery Systems Produced with Supercritical CO2—A Green Future for Particle Formulation?

G Gangapurwala, A Vollrath, A De San Luis… - Pharmaceutics, 2020‏ - mdpi.com
Supercritical carbon dioxide (SC-CO2) can serve as solvent, anti-solvent and solute, among
others, in the field of drug delivery applications, eg, for the formulation of polymeric …