The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …
the association between selected minerals and trace elements and osteoporosis, as well as …
Progress of signaling pathways, stress pathways and epigenetics in the pathogenesis of skeletal fluorosis
L Qiao, X Liu, Y He, J Zhang, H Huang, W Bian… - International journal of …, 2021 - mdpi.com
Fluorine is widely dispersed in nature and has multiple physiological functions. Although it is
usually regarded as an essential trace element for humans, this view is not held universally …
usually regarded as an essential trace element for humans, this view is not held universally …
Enamel phenotypes: genetic and environmental determinants
JT Wright - Genes, 2023 - mdpi.com
Dental enamel is a specialized tissue that has adapted over millions of years of evolution to
enhance the survival of a variety of species. In humans, enamel evolved to form the exterior …
enhance the survival of a variety of species. In humans, enamel evolved to form the exterior …
Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches
Fluoride is a natural element essential in minute quantities in human's to maintain dental
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …
Fluoride impairs ovary development by affecting oogenesis and inducing oxidative stress and apoptosis in female zebrafish (Danio rerio)
M Li, J Cao, Y Zhao, P Wu, X Li, F Khodaei, Y Han… - Chemosphere, 2020 - Elsevier
Previous studies have shown that waterborne fluoride exposure has adverse effects on the
reproductive system of zebrafish. However, the underlying toxic mechanisms were still not …
reproductive system of zebrafish. However, the underlying toxic mechanisms were still not …
[HTML][HTML] Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats
H Li, J Fan, Y Zhao, J Yang, H Xu, RK Manthari… - Ecotoxicology and …, 2021 - Elsevier
Long-term excessive intake of fluoride (F) can cause osseous and non-osseous damage.
The kidney is the main fluoride excretion organ of the body. This study aimed to explore …
The kidney is the main fluoride excretion organ of the body. This study aimed to explore …
[HTML][HTML] Molecular basis of fluoride toxicities: beyond benefits and implications in human disorders
P Pal, NK Jha, D Pal, SK Jha, U Anand… - Genes & …, 2023 - Elsevier
Detrimental impacts of fluoride have become a global concern for several decades. Despite
its beneficial role which is restricted only in skeletal tissues, deleterious effects are also …
its beneficial role which is restricted only in skeletal tissues, deleterious effects are also …
[PDF][PDF] Fluoride contamination, toxicity and its potential therapeutic agents
Fluoride is the thirteenth most abundant element in the earth's crust. It is highly
electronegative and distributed ubiquitously in nature. During weathering of rocks and soil …
electronegative and distributed ubiquitously in nature. During weathering of rocks and soil …
Advances in nutritional epigenetics—A fresh perspective for an old idea. Lessons learned, limitations, and future directions
L Sedley - Epigenetics Insights, 2020 - journals.sagepub.com
Nutritional epigenetics is a rapidly expanding field of research, and the natural modulation of
the genome is a non-invasive, sustainable, and personalized alternative to gene-editing for …
the genome is a non-invasive, sustainable, and personalized alternative to gene-editing for …
Selenomethionine supplementation mitigates fluoride-induced liver apoptosis and inflammatory reactions by blocking Parkin-mediated mitophagy in mice
T Wang, H Li, Y Li, M Li, H Zhao, W Zhang… - Science of The Total …, 2024 - Elsevier
As an environmental pollutant, fluoride-induced liver damage is directly linked to
mitochondrial alteration and oxidative stress. Selenium's antioxidant capacity has been …
mitochondrial alteration and oxidative stress. Selenium's antioxidant capacity has been …