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Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR
T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …
biology. While NMR can provide invaluable information about local geometry on an atomic …
[HTML][HTML] Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR
ASL Thankamony, JJ Wittmann, M Kaushik… - Progress in nuclear …, 2017 - Elsevier
The field of dynamic nuclear polarization has undergone tremendous developments and
diversification since its inception more than 6 decades ago. In this review we provide an in …
diversification since its inception more than 6 decades ago. In this review we provide an in …
Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …
investigation of biological systems within their native context, such as lipid membranes, viral …
Highly efficient, water‐soluble polarizing agents for dynamic nuclear polarization at high frequency
C Sauvée, M Rosay, G Casano… - Angewandte Chemie …, 2013 - Wiley Online Library
Dynamic nuclear polarization coupled to solid-state NMR spectroscopy (DNP/ssNMR) is
emerging as a very powerful technique to overcome the limitations resulting from the …
emerging as a very powerful technique to overcome the limitations resulting from the …
Solid-state NMR studies of amyloid fibril structure
R Tycko - Annual review of physical chemistry, 2011 - annualreviews.org
Current interest in amyloid fibrils stems from their involvement in neurodegenerative and
other diseases and from their role as an alternative structural state for many peptides and …
other diseases and from their role as an alternative structural state for many peptides and …
Surface enhanced NMR spectroscopy by dynamic nuclear polarization
It is shown that surface NMR spectra can be greatly enhanced using dynamic nuclear
polarization. Polarization is transferred from the protons of the solvent to the rare nuclei …
polarization. Polarization is transferred from the protons of the solvent to the rare nuclei …
Direct observation of hierarchical protein dynamics
One of the fundamental challenges of physical biology is to understand the relationship
between protein dynamics and function. At physiological temperatures, functional motions …
between protein dynamics and function. At physiological temperatures, functional motions …
High-resolution NMR studies of antibiotics in cellular membranes
J Medeiros-Silva, S Jekhmane, AL Paioni… - Nature …, 2018 - nature.com
The alarming rise of antimicrobial resistance requires antibiotics with unexploited
mechanisms. Ideal templates could be antibiotics that target the peptidoglycan precursor …
mechanisms. Ideal templates could be antibiotics that target the peptidoglycan precursor …
Dipolar Recoupling in Rotating Solids
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) has evolved significantly
over the past three decades and established itself as a vital tool for the structural analysis of …
over the past three decades and established itself as a vital tool for the structural analysis of …
Dynamic nuclear polarization of amyloidogenic peptide nanocrystals: GNNQQNY, a core segment of the yeast prion protein Sup35p
Dynamic nuclear polarization (DNP) permits a∼ 102− 103 enhancement of the nuclear spin
polarization and therefore increases sensitivity in nuclear magnetic resonance (NMR) …
polarization and therefore increases sensitivity in nuclear magnetic resonance (NMR) …