[HTML][HTML] Insights into CSF-1R expression in the tumor microenvironment
C Tomassetti, G Insinga, F Gimigliano, A Morrione… - Biomedicines, 2024 - mdpi.com
The colony-stimulating factor 1 receptor (CSF-1R) plays a pivotal role in orchestrating
cellular interactions within the tumor microenvironment (TME). Although the CSF-1R has …
cellular interactions within the tumor microenvironment (TME). Although the CSF-1R has …
Advances in and prospects of immunotherapy for prostate cancer
D Liu, L Wang, Y Guo - Cancer Letters, 2024 - Elsevier
Immunotherapy has shown promising therapeutic effects in hematological malignancies and
certain solid tumors and has emerged as a critical and highly potential treatment modality for …
certain solid tumors and has emerged as a critical and highly potential treatment modality for …
[HTML][HTML] Non-coding rna in tumor cells and tumor-associated myeloid cells—function and therapeutic potential
AK Binder, F Bremm, J Dörrie, N Schaft - International Journal of …, 2024 - mdpi.com
The RNA world is wide, and besides mRNA, there is a variety of other RNA types, such as
non-coding (nc) RNAs, which harbor various intracellular regulatory functions. This review …
non-coding (nc) RNAs, which harbor various intracellular regulatory functions. This review …
[HTML][HTML] A Subtype Specific Probe for Targeted Magnetic Resonance Imaging of M2 Tumor-Associated Macrophages in Brain Tumors
Y Li, AM Thamizhchelvan, H Ma, J Padelford, Z Zhang… - Acta Biomaterialia, 2025 - Elsevier
Pro-tumoral M2 tumor-associated macrophages (TAMs) play a critical role in the tumor
immune microenvironment (TIME), making them an important therapeutic target for cancer …
immune microenvironment (TIME), making them an important therapeutic target for cancer …
Chitosan-based nanoarchitectures for siRNA delivery in cancer therapy: A review of pre-clinical and clinical importance
X Bian, X Yu, S Lu, L Jia, P Li, J Yin, S Tan - International Journal of …, 2024 - Elsevier
The gene therapy has been developed into a new cancer treatment option. Now that we
know which molecular components contribute to carcinogenesis, we may use gene therapy …
know which molecular components contribute to carcinogenesis, we may use gene therapy …
[HTML][HTML] The Many Faces of Cyclodextrins within Self-Assembling Polymer Nanovehicles: From Inclusion Complexes to Valuable Structural and Functional Elements
I Jarak, S Ramos, B Caldeira, C Domingues… - International Journal of …, 2024 - mdpi.com
Most chemotherapeutic agents are poorly soluble in water, have low selectivity, and cannot
reach the tumor in the desired therapeutic concentration. On the other hand, sensitive …
reach the tumor in the desired therapeutic concentration. On the other hand, sensitive …
Transforming Cancer Immunotherapy: Overcoming Immunosuppression in Tumors via Gene Silencing Techniques Based on Nanoparticles
Immunotherapy has transformed cancer treatment, but the tumor immune microenvironment
(TIME) is highly immunosuppressive, limiting the effectiveness of immunotherapy and …
(TIME) is highly immunosuppressive, limiting the effectiveness of immunotherapy and …
[HTML][HTML] Enhancing cancer immunotherapy: Nanotechnology-mediated immunotherapy overcoming immunosuppression
Y Chen, Q Zhou, Z Jia, N Cheng, S Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Immunotherapy is an important cancer treatment method that offers hope for curing cancer
patients. While immunotherapy has achieved initial success, a major obstacle to its …
patients. While immunotherapy has achieved initial success, a major obstacle to its …
The heterogeneity of tumor-associated macrophages and strategies to target it.
HAO LV, B Zhu, D Chen - Biocell, 2024 - search.ebscohost.com
Tumor-associated macrophages (TAMs) are emerging as targets for tumor therapy because
of their primary role in promoting tumor progression. Several studies have been conducted …
of their primary role in promoting tumor progression. Several studies have been conducted …