Tuft cells are found in tissues with distinct stem cell compartments, tissue architecture, and
luminal exposures but converge on a shared transcriptional program, including expression …

Pulmonary fibrosis comprises a range of chronic interstitial lung diseases (ILDs) that impose
a significant burden on patients and public health. Among these, idiopathic pulmonary …

Lung injury activates epithelial stem or progenitor cells for alveolar repair and regeneration.
Unraveling the origin and fate of injury-induced progenitors is crucial for elucidating lung …

Severe viral pneumonia can induce rapid expansion of KRT5+ basal-like cells in small
airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and …

Tuft cells are a rare and morphologically distinct chemosensory cell type found throughout
many organs, including the gastrointestinal tract. These cells were identified by their unique …

Histological and lineage immunofluorescence examination revealed that healthy conducting
airways of humans and animals harbor sporadic poorly differentiated epithelial patches …

Tuft cells are chemosensory epithelial cells in the respiratory tract and several other organs.
Recent studies revealed tuft cell-like gene expression signatures in some pulmonary …

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease in which
repetitive epithelial injury and incomplete alveolar repair result in accumulation of profibrotic …

During recent years chemosensory cells in extraoral tissues have been established as
mediators for the detection and regulation of innate immune processes in response to …

The vagal nerve is linked to tumorigenesis in multiple tissues, including small cell lung
cancer (SCLC). However, the role of sympathetic neurons in SCLC development remains …