Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Pyroptosis‐mediated synergistic photodynamic and photothermal immunotherapy enabled by a tumor‐membrane‐targeted photosensitive dimer

Y Tang, HK Bisoyi, XM Chen, Z Liu, X Chen… - Advanced …, 2023 - Wiley Online Library
Overcoming the resistance to apoptosis and immunosuppression of tumor cells is a
significant challenge in augmenting the effect of cancer immunotherapy. Pyroptosis, a lytic …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

Recent advances of AIE light-up probes for photodynamic therapy

S Liu, G Feng, BZ Tang, B Liu - Chemical science, 2021 - pubs.rsc.org
As a new non-invasive treatment method, photodynamic therapy (PDT) has attracted great
attention in biomedical applications. The advantages of possessing fluorescence for …

Aggregation‐induced emission: recent advances in materials and biomedical applications

X Cai, B Liu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
The concept of aggregation‐induced emission (AIE) has opened new opportunities in many
research fields. Motivated by the unique feature of AIE fluorogens (AIEgens), during the past …

ESIPT‐based AIE luminogens: Design strategies, applications, and mechanisms

P Zhou, K Han - Aggregate, 2022 - Wiley Online Library
In this review, we present a systematic and comprehensive summary of the recent
development and applications of excited‐state intramolecular proton transfer‐based (ESIPT …

Emerging strategies in enhancing singlet oxygen generation of nano-photosensitizers toward advanced phototherapy

M Tavakkoli Yaraki, B Liu, YN Tan - Nano-micro letters, 2022 - Springer
The great promise of photodynamic therapy (PDT) has thrusted the rapid progress of
develo** highly effective photosensitizers (PS) in killing cancerous cells and bacteria. To …

Mitochondria-targeted smart AIEgens: Imaging and therapeutics

H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia… - Coordination Chemistry …, 2022 - Elsevier
Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

Supramolecular materials based on AIE luminogens (AIEgens): construction and applications

J Li, J Wang, H Li, N Song, D Wang… - Chemical Society …, 2020 - pubs.rsc.org
The emergence of aggregation-induced emission luminogens (AIEgens) has significantly
stimulated the development of luminescent supramolecular materials because their strong …