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Review of machine learning methods for RNA secondary structure prediction
Q Zhao, Z Zhao, X Fan, Z Yuan, Q Mao… - PLoS computational …, 2021 - journals.plos.org
Secondary structure plays an important role in determining the function of noncoding RNAs.
Hence, identifying RNA secondary structures is of great value to research. Computational …
Hence, identifying RNA secondary structures is of great value to research. Computational …
[HTML][HTML] Predicting RNA secondary structures from sequence and probing data
RNA secondary structures have proven essential for understanding the regulatory functions
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …
The vienna RNA websuite
Abstract The Vienna RNA Websuite is a comprehensive collection of tools for folding, design
and analysis of RNA sequences. It provides a web interface to the most commonly used …
and analysis of RNA sequences. It provides a web interface to the most commonly used …
CONTRAfold: RNA secondary structure prediction without physics-based models
Motivation: For several decades, free energy minimization methods have been the dominant
strategy for single sequence RNA secondary structure prediction. More recently, stochastic …
strategy for single sequence RNA secondary structure prediction. More recently, stochastic …
The ViennaRNA web services
The ViennaRNA package is a widely used collection of programs for thermodynamic RNA
secondary structure prediction. Over the years, many additional tools have been developed …
secondary structure prediction. Over the years, many additional tools have been developed …
A coarse graining method for the identification of transition rates between molecular conformations
S Kube, M Weber - The Journal of chemical physics, 2007 - pubs.aip.org
The coarse graining method to be advocated in this paper consists of two main steps. First,
the propagation of an ensemble of molecular states is described as a Markov chain by a …
the propagation of an ensemble of molecular states is described as a Markov chain by a …
Complex RNA folding kinetics revealed by single-molecule FRET and hidden Markov models
We have developed a hidden Markov model and optimization procedure for photon-based
single-molecule FRET data, which takes into account the trace-dependent background …
single-molecule FRET data, which takes into account the trace-dependent background …
In silico approaches to RNA aptamer design
M Hamada - Biochimie, 2018 - Elsevier
RNA aptamers are ribonucleic acids that bind to specific target molecules. An RNA aptamer
for a disease-related protein has great potential for development into a new drug. However …
for a disease-related protein has great potential for development into a new drug. However …
NMR structural profiling of transcriptional intermediates reveals riboswitch regulation by metastable RNA conformations
Gene repression induced by the formation of transcriptional terminators represents a prime
example for the coupling of RNA synthesis, folding, and regulation. In this context, map** …
example for the coupling of RNA synthesis, folding, and regulation. In this context, map** …
Folding kinetics of large RNAs
We introduce here a heuristic approach to kinetic RNA folding that constructs secondary
structures by stepwise combination of building blocks. These blocks correspond to …
structures by stepwise combination of building blocks. These blocks correspond to …