[HTML][HTML] A review of ensemble learning and data augmentation models for class imbalanced problems: combination, implementation and evaluation

AA Khan, O Chaudhari, R Chandra - Expert Systems with Applications, 2024 - Elsevier
Class imbalance (CI) in classification problems arises when the number of observations
belonging to one class is lower than the other. Ensemble learning combines multiple models …

Machine learning approaches and databases for prediction of drug–target interaction: a survey paper

M Bagherian, E Sabeti, K Wang… - Briefings in …, 2021 - academic.oup.com
The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …

Machine learning for drug-target interaction prediction

R Chen, X Liu, S **, J Lin, J Liu - Molecules, 2018 - mdpi.com
Identifying drug-target interactions will greatly narrow down the scope of search of candidate
medications, and thus can serve as the vital first step in drug discovery. Considering that in …

Computational prediction of drug–target interactions using chemogenomic approaches: an empirical survey

A Ezzat, M Wu, XL Li, CK Kwoh - Briefings in bioinformatics, 2019 - academic.oup.com
Computational prediction of drug–target interactions (DTIs) has become an essential task in
the drug discovery process. It narrows down the search space for interactions by suggesting …

DTI-CDF: a cascade deep forest model towards the prediction of drug-target interactions based on hybrid features

Y Chu, AC Kaushik, X Wang, W Wang… - Briefings in …, 2021 - academic.oup.com
Drug–target interactions (DTIs) play a crucial role in target-based drug discovery and
development. Computational prediction of DTIs can effectively complement experimental …

[HTML][HTML] A comprehensive review of feature based methods for drug target interaction prediction

K Sachdev, MK Gupta - Journal of biomedical informatics, 2019 - Elsevier
Drug target interaction is a prominent research area in the field of drug discovery. It refers to
the recognition of interactions between chemical compounds and the protein targets in the …

SperoPredictor: an integrated machine learning and molecular docking-based drug repurposing framework with use case of COVID-19

F Ahmed, JW Lee, A Samantasinghar, YS Kim… - Frontiers in public …, 2022 - frontiersin.org
The global spread of the SARS coronavirus 2 (SARS-CoV-2), its manifestation in human
hosts as a contagious disease, and its variants have induced a pandemic resulting in the …

Comparison study of computational prediction tools for drug-target binding affinities

M Thafar, AB Raies, S Albaradei, M Essack… - Frontiers in …, 2019 - frontiersin.org
The drug development is generally arduous, costly, and success rates are low. Thus, the
identification of drug-target interactions (DTIs) has become a crucial step in early stages of …

ADMET evaluation in drug discovery. 19. Reliable prediction of human cytochrome P450 inhibition using artificial intelligence approaches

Z Wu, T Lei, C Shen, Z Wang, D Cao… - Journal of chemical …, 2019 - ACS Publications
Adverse effects induced by drug–drug interactions may result in early termination of drug
development or even withdrawal of drugs from the market, and many drug–drug interactions …

DTI-MLCD: predicting drug-target interactions using multi-label learning with community detection method

Y Chu, X Shan, T Chen, M Jiang, Y Wang… - Briefings in …, 2021 - academic.oup.com
Identifying drug-target interactions (DTIs) is an important step for drug discovery and drug
repositioning. To reduce the experimental cost, a large number of computational …