Uterine fibroids

EA Stewart, SK Laughlin-Tommaso… - Nature reviews Disease …, 2016‏ - nature.com
Uterine fibroids (also known as leiomyomas or myomas) are common clonal neoplasms of
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …

Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics

MS Islam, A Ciavattini, F Petraglia… - Human reproduction …, 2018‏ - academic.oup.com
BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

Uterine fibroids

SE Bulun - New England Journal of Medicine, 2013‏ - Mass Medical Soc
Uterine Fibroids | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer

JJ Kim, T Kurita, SE Bulun - Endocrine reviews, 2013‏ - academic.oup.com
Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …

[HTML][HTML] Ulipristal acetate versus placebo for fibroid treatment before surgery

J Donnez, TF Tatarchuk, P Bouchard… - … England Journal of …, 2012‏ - Mass Medical Soc
Background The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic
uterine fibroids before surgery are uncertain. Methods We randomly assigned women with …

Ulipristal acetate versus leuprolide acetate for uterine fibroids

J Donnez, J Tomaszewski, F Vázquez… - … England Journal of …, 2012‏ - Mass Medical Soc
Background The efficacy and side-effect profile of ulipristal acetate as compared with those
of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are …

Uterine fibroids: pathogenesis and interactions with endometrium and endomyometrial junction

A Ciavattini, J Di Giuseppe, P Stortoni… - Obstetrics and …, 2013‏ - Wiley Online Library
Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically
apparent in a large part of reproductive aged women. Clinically, they present with a variety …

[HTML][HTML] Efficacy and safety of repeated use of ulipristal acetate in uterine fibroids

J Donnez, R Hudecek, O Donnez, D Matule… - Fertility and sterility, 2015‏ - Elsevier
Objective To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg
daily of ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. Design …

Selective progesterone receptor modulators—mechanisms and therapeutic utility

MS Islam, S Afrin, SI Jones, J Segars - Endocrine Reviews, 2020‏ - academic.oup.com
Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Uterine leiomyoma: available medical treatments and new possible therapeutic options

MS Islam, O Protic, SR Giannubilo, P Toti… - The Journal of …, 2013‏ - academic.oup.com
Context: Uterine leiomyomas (fibroids or myomas) are benign tumors of the uterus and are
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …