trRosettaRNA: automated prediction of RNA 3D structure with transformer network
RNA 3D structure prediction is a long-standing challenge. Inspired by the recent
breakthrough in protein structure prediction, we developed trRosettaRNA, an automated …
breakthrough in protein structure prediction, we developed trRosettaRNA, an automated …
Machine learning for RNA 2D structure prediction benchmarked on experimental data
Since the 1980s, dozens of computational methods have addressed the problem of
predicting RNA secondary structure. Among them are those that follow standard optimization …
predicting RNA secondary structure. Among them are those that follow standard optimization …
Has AlphaFold 3 reached its success for RNAs?
Predicting the 3D structure of RNA is a significant challenge despite ongoing advancements
in the field. Although AlphaFold has successfully addressed this problem for proteins, RNA …
in the field. Although AlphaFold has successfully addressed this problem for proteins, RNA …
Comparative analysis of RNA 3D structure prediction methods: towards enhanced modeling of RNA–ligand interactions
Accurate RNA structure models are crucial for designing small molecule ligands that
modulate their functions. This study assesses six standalone RNA 3D structure prediction …
modulate their functions. This study assesses six standalone RNA 3D structure prediction …
RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction
Motivation Predicting the 3D structure of RNA is an ongoing challenge that has yet to be
completely addressed despite continuous advancements. RNA 3D structures rely on …
completely addressed despite continuous advancements. RNA 3D structures rely on …
[HTML][HTML] ModelCIF: An extension of PDBx/mmCIF data representation for computed structure models
Abstract ModelCIF (github. com/ihmwg/ModelCIF) is a data information framework
developed for and by computational structural biologists to enable delivery of Findable …
developed for and by computational structural biologists to enable delivery of Findable …
Advancing RNA 3D structure prediction: Exploring hierarchical and hybrid approaches in CASP15
In CASP15, we used an integrated hierarchical and hybrid approach to predict RNA
structures. The approach involves three steps. First, with the use of physics‐based methods …
structures. The approach involves three steps. First, with the use of physics‐based methods …
[HTML][HTML] Discovery of a trefoil knot in the RydC RNA: Challenging previous notions of RNA topology
Knots are very common in polymers, including DNA and protein molecules. Yet, no genuine
knot has been identified in natural RNA molecules to date. Upon re-examining …
knot has been identified in natural RNA molecules to date. Upon re-examining …
Computational modeling of DNA 3D structures: From dynamics and mechanics to folding
DNA carries the genetic information required for the synthesis of RNA and proteins and
plays an important role in many processes of biological development. Understanding the …
plays an important role in many processes of biological development. Understanding the …
[HTML][HTML] mRNA vaccine sequence and structure design and optimization: Advances and challenges
L **, Y Zhou, S Zhang, SJ Chen - Journal of Biological Chemistry, 2024 - Elsevier
Messenger RNA (mRNA) vaccines have emerged as a powerful tool against communicable
diseases and cancers, as demonstrated by their huge success during the coronavirus …
diseases and cancers, as demonstrated by their huge success during the coronavirus …