Human dorsal root ganglia

RV Haberberger, C Barry, N Dominguez… - Frontiers in cellular …, 2019 - frontiersin.org
Sensory neurons with cell bodies situated in dorsal root ganglia convey information from
external or internal sites of the body such as actual or potential harm, temperature or muscle …

Copper induces cognitive impairment in mice via modulation of cuproptosis and CREB signaling

Y Zhang, Q Zhou, L Lu, Y Su, W Shi, H Zhang, R Liu… - Nutrients, 2023 - mdpi.com
It has been reported that disordered Cu metabolism is associated with several
neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease …

[HTML][HTML] PC12 cell line: cell types, coating of culture vessels, differentiation and other culture conditions

B Wiatrak, A Kubis-Kubiak, A Piwowar, E Barg - Cells, 2020 - mdpi.com
The PC12 cell line is one of the most commonly used in neuroscience research, including
studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and …

[HTML][HTML] Overview of evidence-based chemotherapy for oral cancer: focus on drug resistance related to the epithelial-mesenchymal transition

J Sha, Y Bai, HX Ngo, T Okui, T Kanno - Biomolecules, 2021 - mdpi.com
The increasing incidence of resistance to chemotherapeutic agents has become a major
issue in the treatment of oral cancer (OC). Epithelial-mesenchymal transition (EMT) has …

Tunable hydrogel viscoelasticity modulates human neural maturation

JG Roth, MS Huang, RS Navarro, JT Akram… - Science …, 2023 - science.org
Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising in vitro model
system for studying neurodevelopment. However, current models remain limited in their …

α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson's disease

FF Geibl, MT Henrich, Z **e, E Zampese… - Molecular …, 2024 - Springer
Background Pathological accumulation of aggregated α-synuclein (aSYN) is a common
feature of Parkinson's disease (PD). However, the mechanisms by which intracellular aSYN …

An Antisense Oligonucleotide-Loaded Blood–Brain Barrier Penetrable Nanoparticle Mediating Recruitment of Endogenous Neural Stem Cells for the Treatment of …

Y Sun, J Kong, X Ge, M Mao, H Yu, Y Wang - ACS nano, 2023 - ACS Publications
Parkinson's disease (PD) is a neurodegenerative disease characterized by the death of
dopaminergic (DA) neurons and currently cannot be cured. One selected antisense …

[HTML][HTML] Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas

RH Kofoed, CL Dibia, K Noseworthy, K Xhima… - Journal of Controlled …, 2022 - Elsevier
Focused ultrasound combined with intravenously injected microbubbles (FUS) is known to
non-invasively, locally, and transiently increase the permeability of the blood-brain barrier …

Human umbilical cord mesenchymal stem cells-derived extracellular vesicles facilitate the repair of spinal cord injury via the miR-29b-3p/PTEN/Akt/mTOR axis

X **ao, W Li, D Rong, Z Xu, Z Zhang, H Ye, L **e… - Cell Death …, 2021 - nature.com
Spinal cord injury (SCI) is a salient traumatic disease that often leads to permanent
disability, and motor and sensory impairments. Human umbilical cord mesenchymal stem …

RANBP17 overexpression restores nucleocytoplasmic transport and ameliorates neurodevelopment in induced DYT1 dystonia motor neurons

M Akter, H Cui, MA Hosain, J Liu, Y Duan… - Journal of …, 2024 - jneurosci.org
DYT1 dystonia is a debilitating neurological movement disorder, and it represents the most
frequent and severe form of hereditary primary dystonia. There is currently no cure for this …