Integrative regulation of human brain blood flow

CK Willie, YC Tzeng, JA Fisher… - The Journal of …, 2014 - Wiley Online Library
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

[HTML][HTML] 4D flow imaging with MRI

Z Stankovic, BD Allen, J Garcia, KB Jarvis… - … diagnosis and therapy, 2014 - ncbi.nlm.nih.gov
Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation
of patients with cardiovascular disease. Since its introduction in the late 1980s, 2 …

Increased cerebral arterial pulsatility in patients with leukoaraiosis: arterial stiffness enhances transmission of aortic pulsatility

AJS Webb, M Simoni, S Mazzucco, W Kuker, U Schulz… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Arterial stiffening reduces dam** of the arterial waveform and
hence increases pulsatility of cerebral blood flow, potentially damaging small vessels. In the …

Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Age, sex, and the vascular contributors to cerebral pulsatility and pulsatile dam**

WK Lefferts, JP DeBlois, JA Augustine… - Journal of Applied …, 2020 - journals.physiology.org
Cerebral pulsatility reflects a balance between the transmission and dam** of pulsatility in
the cerebrovasculature. Females experience greater cerebral pulsatility with aging, which …

Aging alters the dampening of pulsatile blood flow in cerebral arteries

L Zarrinkoob, K Ambarki, A Wåhlin… - Journal of Cerebral …, 2016 - journals.sagepub.com
Excessive pulsatile flow caused by aortic stiffness is thought to be a contributing factor for
several cerebrovascular diseases. The main purpose of this study was to describe the …

Changes in intracranial venous blood flow and pulsatility in Alzheimer's disease: A 4D flow MRI study

LA Rivera-Rivera, T Schubert, P Turski… - Journal of Cerebral …, 2017 - journals.sagepub.com
Cerebral blood flow, arterial pulsation, and vasomotion may be important indicators of
cerebrovascular health in aging and diseases of aging such as Alzheimer's disease …

Computed tomographic distinction of intimal and medial calcification in the intracranial internal carotid artery

R Kockelkoren, A Vos, W Van Hecke, A Vink… - PloS one, 2017 - journals.plos.org
Background Intracranial internal carotid artery (iICA) calcification is associated with stroke
and is often seen as a proxy of atherosclerosis of the intima. However, it was recently shown …

Understanding intracranial aneurysm sounds via high-fidelity fluid-structure-interaction modelling

DA Bruneau, DA Steinman… - Communications …, 2023 - nature.com
Background Since the 1960s, the origins of intracranial aneurysm bruits and musical
murmurs have been debated, with proposed mechanisms ranging from self-excitation (ie …

Narrowing the expertise gap for predicting intracranial aneurysm hemodynamics: impact of solver numerics versus mesh and time-step resolution

MO Khan, K Valen-Sendstad… - American journal of …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent high-resolution computational fluid dynamics
studies have uncovered the presence of laminar flow instabilities and possible transitional or …