Network representation of multicellular activity in pancreatic islets: Technical considerations for functional connectivity analysis

M Šterk, Y Zhang, V Pohorec, EP Leitgeb… - PLOS Computational …, 2024 - journals.plos.org
Within the islets of Langerhans, beta cells orchestrate synchronized insulin secretion, a
pivotal aspect of metabolic homeostasis. Despite the inherent heterogeneity and multimodal …

[HTML][HTML] Beyond Glycemic Control: GLP-1 Receptor Agonists and Their Impact on Calcium Homeostasis in Real-World Patients

BT Alenezi, N Elfezzani, R Uddin, H Patel… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: The effect of glucagon-like peptide-1 receptor (GLP-1R) agonists on
calcium homeostasis is poorly understood. This study aimed to investigate the association …

Calcium Imaging and Analysis in Beta Cells in Acute Mouse Pancreas Tissue Slices

E Paradiž Leitgeb, V Pohorec… - … Signaling: Methods and …, 2024 - Springer
Ca2+ ions play a central role in the stimulus-secretion coupling cascade of pancreatic beta
cells. The use of confocal microscopy in conjunction with the acute pancreas tissue slice …