Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Acute myeloid leukemia: the good, the bad, and the ugly
Acute myeloid leukemia (AML) was initially subdivided according to morphology (the French-
American-British system), which proved helpful in pathologic categorization. Subsequently …
American-British system), which proved helpful in pathologic categorization. Subsequently …
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
The emerging" epitranscriptomics" field is providing insights into the biological and
pathological roles of different RNA modifications. The RNA methyltransferase METTL1 …
pathological roles of different RNA modifications. The RNA methyltransferase METTL1 …
AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms
Abstract The chromosomal translocation t (8; 21) and the resulting oncofusion gene
AML1/ETO have long served as a prototypical genetic lesion to model and understand …
AML1/ETO have long served as a prototypical genetic lesion to model and understand …
Targeting an RNA-binding protein network in acute myeloid leukemia
RNA-binding proteins (RBPs) are essential modulators of transcription and translation
frequently dysregulated in cancer. We systematically interrogated RBP dependencies in …
frequently dysregulated in cancer. We systematically interrogated RBP dependencies in …
The genomic landscape of core-binding factor acute myeloid leukemias
Acute myeloid leukemia (AML) comprises a heterogeneous group of leukemias frequently
defined by recurrent cytogenetic abnormalities, including rearrangements involving the core …
defined by recurrent cytogenetic abnormalities, including rearrangements involving the core …
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly
because of the lack of actionable immune targets. Using an original proteogenomic …
because of the lack of actionable immune targets. Using an original proteogenomic …
Genomic landscape and clonal evolution of acute myeloid leukemia with t (8; 21): an international study on 331 patients
Acute myeloid leukemia with t (8; 21)(q22; q22) is characterized by considerable clinical and
biological heterogeneity leading to relapse in up to 40% of patients. We sequenced coding …
biological heterogeneity leading to relapse in up to 40% of patients. We sequenced coding …
[HTML][HTML] Immunotherapeutic targeting of surfaceome heterogeneity in AML
Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other
hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic …
hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic …
The clinical mutatome of core binding factor leukemia
The fusion genes CBFB/MYH11 and RUNX1/RUNX1T1 block differentiation through
disruption of the core binding factor (CBF) complex and are found in 10–15% of adult de …
disruption of the core binding factor (CBF) complex and are found in 10–15% of adult de …
Scalable prediction of acute myeloid leukemia using high-dimensional machine learning and blood transcriptomics
Acute myeloid leukemia (AML) is a severe, mostly fatal hematopoietic malignancy. We were
interested in whether transcriptomic-based machine learning could predict AML status …
interested in whether transcriptomic-based machine learning could predict AML status …