Cardiovascular surgery and organ damage: time to reconsider the role of hemolysis

ICV Windsant, SJ Hanssen, WA Buurman… - The Journal of thoracic …, 2011 - jtcvs.org
Cardiovascular surgery with cardiopulmonary bypass is associated with postoperative organ
injury, which severely affects patient morbidity and mortality. Multiple cardiopulmonary …

Haemolysis in haemodialysis

D Tharmaraj, PG Kerr - Nephrology, 2017 - Wiley Online Library
Haemolysis in haemodialysis, although rare in current times, is associated with significant
mortality and morbidity. As such prompt recognition, treatment, analysis of root cause and …

Haptoglobin or hemopexin therapy prevents acute adverse effects of resuscitation after prolonged storage of red cells

JA Graw, C Mayeur, I Rosales, Y Liu, VS Sabbisetti… - Circulation, 2016 - Am Heart Assoc
Background: Extracellular hemoglobin and cell-free heme are toxic breakdown products of
hemolyzed erythrocytes. Mammals synthesize the scavenger proteins haptoglobin and …

Age of red cells for transfusion and outcomes in patients with ARDS

JA Graw, V Bünger, LA Materne, A Krannich… - Journal of Clinical …, 2022 - mdpi.com
Packed red blood cells (PRBCs), stored for prolonged intervals, might contribute to adverse
clinical outcomes in critically ill patients. In this study, short-term outcome after transfusion of …

Enhancing nitrite reductase activity of modified hemoglobin: bis-tetramers and their PEGylated derivatives

FE Lui, R Kluger - Biochemistry, 2009 - ACS Publications
The clinical evaluation of stabilized tetrameric hemoglobin as alternatives to red cells
revealed that the materials caused significant increases in blood pressure and related …

Shortened red blood cell age in patients with end-stage renal disease who were receiving haemodialysis: a cross-sectional study

K Matsumura, T Okumiya, T Sugiura, N Takahashi… - BMC nephrology, 2020 - Springer
Background The causes of anaemia in patients with end-stage renal disease include a
relative deficiency in erythropoietin production and complex clinical conditions. We aimed to …

[HTML][HTML] Prognostic biomarkers in ST-segment elevation myocardial infarction: a step toward personalized medicine or a tool in search of an application?

LM Biasucci, R Della Bona - Journal of the American College of Cardiology, 2011 - jacc.org
In recent years, much effort has been devoted to risk stratification of patients with acute
coronary syndromes (ACS), mainly focusing on patients with non–ST-segment elevation …

Die Bedeutung der Hämolyse in Anästhesie und Intensivmedizin

JA Graw, DM Baron, RCE Francis - AINS-Anästhesiologie …, 2018 - thieme-connect.com
Die intravasale Hämolyse mit erhöhten Plasmakonzentrationen von zellfreiem Hämoglobin
tritt nicht nur bei hämolytischen Erkrankungen auf–sie ist auch bei der Transfusion von …

Treatment of advanced group 2 PH

CF Barnett, T De Marco - Progress in Cardiovascular Diseases, 2016 - Elsevier
Pulmonary hypertension (PH) frequently occurs in patients with left heart disease (LHD),
including heart failure with reduced and preserved ejection fraction and valvular heart …

[PDF][PDF] Haemolysis in Patients with End-Stage Renal Disease Receiving Haemodialysis: A Cross-Sectional Study

K Matsumura, T Okumiya, T Sugiura, N Takahashi… - 2020 - scholar.archive.org
Background: Haemolysis due to mechanical stress on red blood cells (RBCs) during
extracorporeal circulation has been reported in patients receiving haemodialysis. However …