The convergence of advances in medical science, human biology, data science, and
technology has enabled the generation of new insights into the phenotype known as …

Patients with type 2 diabetes mellitus (T2DM) are at high risk for macrovascular
complications, which represent the major cause of mortality. Despite effective treatment of …

Metabolic responses to food influence risk of cardiometabolic disease, but large-scale high-
resolution studies are lacking. We recruited n= 1,002 twins and unrelated healthy adults in …

Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Aging and diabetes mellitus are 2 well-known risk factors for cardiovascular disease (CVD).
During the past 50 years, there has been an dramatic increase in life expectancy with a …

Endothelial dysfunction is one of the initial steps in the pathogenesis of atherosclerosis and
development of cardiovascular disease in patients with diabetes mellitus. Several risk …

Objectives To evaluate associations between different definitions of prediabetes and the risk
of cardiovascular disease and all cause mortality. Design Meta-analysis of prospective …

Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by
glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10 …

Type 2 diabetes mellitus (T2DM) is associated with a two-to four-fold increased risk of
develo** cardiovascular disease (CVD) and microvascular complications, which may …