Membrane transport proteins, also known as transporters, control the movement of ions,
nutrients, metabolites, and waste products across the membranes of a cell and are central to …

Malaria is a major cause of morbidity and mortality. Immunity is acquired but is suboptimal,
being slow to develop and incomplete. An inadequate understanding of natural immunity …

Vaccine development for the blood stages of malaria has focused on the induction of
antibodies to parasite surface antigens, most of which are highly polymorphic. An alternate …

Background The continuing morbidity and mortality associated with infection with malaria
parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in …

The control of diseases caused by protozoan parasites is one of the United Nations'
Sustainable Development Goals. In recent years much research effort has gone into …

The RMgm database, www. pberghei. eu, is a web-based, manually curated, repository
containing information on genetically modified rodent-malaria parasites. It provides easy …

Infection with Plasmodium species parasites causes malaria. Plasmodium parasites are
purine auxotrophs. In all life cycle stages, they require purines for RNA and DNA synthesis …

Infection with malaria parasites continues to be a major global public health issue. While
current control measures have enabled a significant decrease in morbidity and mortality …

Malaria vaccination approaches using live Plasmodium parasites are currently explored,
with either attenuated mosquito-derived sporozoites or attenuated blood-stage parasites …

Despite a century of research focused on the development and implementation of effective
control strategies, infection with the malaria parasite continues to result in significant …