Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …

Ventricular arrhythmias and sudden cardiac death (SCD) occur most frequently in the setting
of coronary artery disease, cardiomyopathy and heart failure but are also increasingly …

Aging is a major risk factor for impaired cardiovascular health. Because the aging
myocardium is characterized by microcirculatory dysfunction, and because nerves align with …

Optical map** is an imaging technique that is extensively used in cardiovascular
research, wherein parameter-sensitive fluorescent indicators are used to study the …

Patients with Type 2 diabetes mellitus (T2DM) frequently exhibit a distinctive cardiac
phenotype known as diabetic cardiomyopathy. Cardiac complications associated with T2DM …

Diabetic cardiomyopathy is defined as the myocardial dysfunction that suffers patients with
diabetes mellitus (DM) in the absence of hypertension and structural heart diseases such as …

Ethnopharmacological relevance Diabetes mellitus-induced erectile dysfunction (DMED) is
one of the most common complications of diabetes mellitus. Leech and centipede granules …

Diabetes mellitus type 2 is associated with adverse clinical outcome after myocardial
infarction. To better understand the underlying causes we here investigated sarcomere …

Prediabetic myocardium, induced by fructose-rich diet (FRD), is prone to increased
sarcoplasmic reticulum (SR)-Ca2+ leak and arrhythmias due to increased activity of the …

Simultaneous activation of the sympathetic and parasympathetic nervous systems is crucial
for the initiation of paroxysmal atrial fibrillation (AF). However, unbalanced activation of the …