Inhibitory feedback control of NF-κB signalling in health and disease

JA Prescott, JP Mitchell, SJ Cook - Biochemical Journal, 2021 - portlandpress.com
Cells must adapt to changes in their environment to maintain cell, tissue and organismal
integrity in the face of mechanical, chemical or microbiological stress. Nuclear factor-κB (NF …

MicroRNAs, new effectors and regulators of NF‐κB

MP Boldin, D Baltimore - Immunological reviews, 2012 - Wiley Online Library
Since its discovery 25 years ago, nuclear factor‐κB (NF‐κB) has emerged as a transcription
factor that controls diverse biological functions, ranging from inflammation to learning and …

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways

A Bhattacharya, JD Ziebarth, Y Cui - Nucleic acids research, 2014 - academic.oup.com
Poly morphisms in mi cro R NAs (miRNAs) and their t arget s ites (PolymiRTS) are known to
disrupt miRNA function, leading to the development of disease and variation in physiological …

MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma

D Li, X Liu, L Lin, J Hou, N Li, C Wang, P Wang… - Journal of Biological …, 2011 - jbc.org
In our in-depth analysis carried out by the Illumina Solexa massive parallel signature
sequencing, microRNA-99a (miR-99a) was found to be the sixth abundant microRNA in the …

Cervical cancer markers: epigenetics and microRNAs

V Laengsri, U Kerdpin, C Plabplueng… - Laboratory …, 2018 - academic.oup.com
Gynecologic malignant neoplasms are a severe health problem among female patients, of
which cervical cancer (CC), in particular, is a common disease leading to high mortality …

miR-146a polymorphism influences levels of miR-146a, IRAK-1, and TRAF-6 in young patients with coronary artery disease

P Ramkaran, S Khan, A Phulukdaree… - Cell biochemistry and …, 2014 - Springer
Modulation of nuclear factor KappaB (NF-κB) activation may play a role in regulating
inflammatory conditions associated with coronary artery disease (CAD). MicroRNA-146a …

Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

SE Löfgren, J Frostegård, L Truedsson… - Genes & …, 2012 - nature.com
A recent genome-wide association study revealed a variant (rs2431697) in an intergenic
region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) …

Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk

K Srivastava, A Srivastava - PloS one, 2012 - journals.plos.org
Background MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of
corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct …

[HTML][HTML] Consequences of genetic variants in miRNA genes

M Machowska, P Galka-Marciniak… - Computational and …, 2022 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that posttranscriptionally regulate the
expression of most genes. They are involved in regulating many physiological processes …

Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies

XP Ma, T Zhang, B Peng, L Yu, DK Jiang - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNA molecules, which participate in diverse
biological processes and may regulate tumor suppressor genes or oncogenes. Single …