Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection
R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …
pandemic—causes reduction of smell and taste in a large fraction of patients. The …
[HTML][HTML] Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms
R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …
examine potential mechanisms that may explain why the sense of smell is lost or altered …
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice
The ongoing coronavirus disease 2019 (COVID-19) pandemic is associated with substantial
morbidity and mortality. Although much has been learned in the first few months of the …
morbidity and mortality. Although much has been learned in the first few months of the …
COVID-19 and the chemical senses: supporting players take center stage
The main neurological manifestation of COVID-19 is loss of smell or taste. The high
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo …
Background Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not
readily achievable with currently approved doses. There is limited evidence to support its …
readily achievable with currently approved doses. There is limited evidence to support its …
Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters
B Bryche, A St Albin, S Murri, S Lacôte, C Pulido… - Brain, behavior, and …, 2020 - Elsevier
Anosmia is one of the most prevalent symptoms of SARS-CoV-2 infection during the COVID-
19 pandemic. However, the cellular mechanism behind the sudden loss of smell has not yet …
19 pandemic. However, the cellular mechanism behind the sudden loss of smell has not yet …
Prevalence of chemosensory dysfunction in COVID-19 patients: a systematic review and meta-analysis reveals significant ethnic differences
CS von Bartheld, MM Hagen… - ACS chemical …, 2020 - ACS Publications
A significant proportion of people who test positive for COVID-19 have chemosensory
deficits. However, the reported prevalence of these deficits in smell and taste varies widely …
deficits. However, the reported prevalence of these deficits in smell and taste varies widely …
Mechanism of anosmia caused by symptoms of COVID-19 and emerging treatments
R Najafloo, J Majidi, A Asghari… - ACS Chemical …, 2021 - ACS Publications
The occurrence of anosmia, the loss or change in sense of smell, is one of the most common
symptoms of COVID-19 experienced by almost 53% of those affected. Several hypotheses …
symptoms of COVID-19 experienced by almost 53% of those affected. Several hypotheses …
[HTML][HTML] Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms-a …
Background: The present study aimed to determine the global prevalence of anosmia and
dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association …
dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association …
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion
The development of a tractable small animal model faithfully reproducing human
coronavirus disease 2019 pathogenesis would arguably meet a pressing need in …
coronavirus disease 2019 pathogenesis would arguably meet a pressing need in …