Natural and experimental SARS-CoV-2 infection in domestic and wild animals

DA Meekins, NN Gaudreault, JA Richt - Viruses, 2021 - mdpi.com
SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic,
which continues to spread with devastating effects on global health and socioeconomics …

Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects

G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …

[HTML][HTML] Evidence for a mouse origin of the SARS-CoV-2 Omicron variant

C Wei, KJ Shan, W Wang, S Zhang, Q Huan… - Journal of genetics and …, 2021 - Elsevier
The rapid accumulation of mutations in the SARS-CoV-2 Omicron variant that enabled its
outbreak raises questions as to whether its proximal origin occurred in humans or another …

The evolutionary drivers and correlates of viral host jumps

CCS Tan, L van Dorp, F Balloux - Nature ecology & evolution, 2024 - nature.com
Most emerging and re-emerging infectious diseases stem from viruses that naturally
circulate in non-human vertebrates. When these viruses cross over into humans, they can …

CATH: increased structural coverage of functional space

I Sillitoe, N Bordin, N Dawson, VP Waman… - Nucleic acids …, 2021 - academic.oup.com
Abstract CATH (https://www. cathdb. info) identifies domains in protein structures from
wwPDB and classifies these into evolutionary superfamilies, thereby providing structural and …

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

Y Liu, G Hu, Y Wang, W Ren, X Zhao, F Ji… - Proceedings of the …, 2021 - pnas.org
The pandemic of COVID-19, caused by SARS-CoV-2, is a major global health threat.
Epidemiological studies suggest that bats (Rhinolophus affinis) are the natural zoonotic …

SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential therapies

AM Almehdi, G Khoder, AS Alchakee, AT Alsayyid… - Infection, 2021 - Springer
Purpose COVID-19 pandemic has emerged as a result of infection by the deadly pathogenic
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …

Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven
a challenge to healthcare systems since its first appearance in late 2019. The global spread …

A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites

MJ Islam, NN Islam, MS Alom, M Kabir, MA Halim - Immunobiology, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, is a highly transmittable and pathogenic human coronavirus that first emerged in …

Transmission of SARS-CoV-2 from humans to animals and potential host adaptation

CCS Tan, SD Lam, D Richard, CJ Owen… - Nature …, 2022 - nature.com
Abstract SARS-CoV-2, the causative agent of the COVID-19 pandemic, can infect a wide
range of mammals. Since its spread in humans, secondary host jumps of SARS-CoV-2 from …