[HTML][HTML] Understanding acquired brain injury: a review

L Goldman, EM Siddiqui, A Khan, S Jahan… - Biomedicines, 2022‏ - mdpi.com
Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI).
In general, ABI does not result from congenital disorders, degenerative diseases, or by brain …

Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024‏ - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Recovery of consciousness after acute brain injury: a narrative review

S Egawa, J Ader, J Claassen - Journal of Intensive Care, 2024‏ - Springer
Abstract Background Disorders of consciousness (DoC) are frequently encountered in both,
acute and chronic brain injuries. In many countries, early withdrawal of life-sustaining …

Therapy of traumatic brain injury by modern agents and traditional Chinese medicine

C Wei, J Wang, J Yu, Q Tang, X Liu, Y Zhang, D Cui… - Chinese medicine, 2023‏ - Springer
Traumatic brain injury (TBI) is the leading cause of disability and death, and the social
burden of mortality and morbidity caused by TBI is significant. Under the influence of …

[HTML][HTML] Amantadine for traumatic brain injury—Supporting evidence and mode of action

A Dekundy, G Pichler, R El Badry, A Scheschonka… - Biomedicines, 2024‏ - mdpi.com
Traumatic brain injury (TBI) is an important global clinical issue, requiring not only
prevention but also effective treatment. Following TBI, diverse parallel and intertwined …

[HTML][HTML] Amantadine for functional improvement in patients with traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis

HFC Siy, MLA Gimenez - Brain and Spine, 2024‏ - Elsevier
Introduction TBIs contribute in over one-third of injury-related deaths with mortality rates as
high as 50% in trauma centers serving the most severe TBI. The effect of TBI on mortality is …

Efficacy of melatonin for prolonged disorders of consciousness: a double-blind, randomized clinical trial

X Wen, J Yu, G Zhu, J Wang, Y Sun, J Zhou, J Cai… - BMC medicine, 2024‏ - Springer
Sleep is essential for the recovery of patients with disorders of consciousness (DoC).
However, few approaches targeting sleep were applied. Melatonin has been shown to …

Pharmacological treatments

E Szymkowicz, N Alnagger… - Coma and disorders of …, 2024‏ - Springer
This chapter reviews the current state of knowledge about pharmacological treatments
acting on the recovery of consciousness in patients with severe brain injury. Potential …

Use of amantadine in traumatic brain injury: an updated meta-analysis of randomized controlled trials

J Félix, L Araújo, A Henriques, A Pereira… - Frontiers in …, 2025‏ - frontiersin.org
Introduction Amantadine has been shown to accelerate cognitive and functional brain
recovery after cerebrovascular accidents. However, the efficacy of this drug in TBI patients …

Breaking barriers in trauma research: a narrative review of opportunities to leverage veterinary trauma for accelerated translation to clinical solutions for pets and …

KE Hall, C Tucker, JA Dunn, T Webb… - Journal of clinical and …, 2024‏ - cambridge.org
Trauma is a common cause of morbidity and mortality in humans and companion animals.
Recent efforts in procedural development, training, quality systems, data collection, and …